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The effect of continuous positive airway pressure on obstructive sleep apnea in children with syndromic craniosynostosis.
Chang, Yuan; Yu, Yongbo; Zhang, Wei; Gao, Yinghui; Feng, Junjun; Li, Mengjie; Han, Fang.
Afiliación
  • Chang Y; Department of Sleep Medicine, Peking University Pepole's Hospital, 11 Xizhimennan Road, Beijing, 100044, China.
  • Yu Y; Sleep Center, Peking University International Hospital, Beijing, China.
  • Zhang W; Sleep Center, Peking University International Hospital, Beijing, China.
  • Gao Y; Sleep Center, Peking University International Hospital, Beijing, China.
  • Feng J; Sleep Center, Peking University International Hospital, Beijing, China.
  • Li M; Sleep Center, Peking University International Hospital, Beijing, China.
  • Han F; Department of Sleep Medicine, Peking University Pepole's Hospital, 11 Xizhimennan Road, Beijing, 100044, China. hanfang1@hotmail.com.
Sleep Breath ; 28(3): 1439-1448, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38180682
ABSTRACT

BACKGROUND:

Obstructive sleep apnea (OSA) is common in children with syndromic craniosynostosis (SC). However, objective data on the treatment of OSA in children with SC remain inadequate. This study aimed to explore the efficacy of continuous positive airway pressure (CPAP) in the management of OSA in children with SC.

METHODS:

A retrospective study was performed in children with SC and OSA diagnosed by polysomnography (PSG), which was defined as an apnea hypopnea index (AHI) ≥ 1. Patients were included if they were treated with CPAP and had baseline PSG and follow-up sleep studies. Clinical and demographic data were collected from all enrolled subjects.

RESULTS:

A total of 45 children with SC and OSA were identified, with an average age of 6.8 ± 4.7 years. Among them, 36 cases had moderate to severe OSA (22 with severe OSA) and received CPAP therapy followed by post-treatment sleep studies. Notably, there was a significant reduction in the AHI observed after CPAP treatment (3.0 [IQR 1.7, 4.6] versus 38.6 [IQR 18.2, 53.3] events/h; P < 0.001).

CONCLUSIONS:

CPAP is effective and acceptable in treating severe OSA in children with SC.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisomnografía / Craneosinostosis / Apnea Obstructiva del Sueño / Presión de las Vías Aéreas Positiva Contínua Tipo de estudio: Observational_studies Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Sleep Breath Asunto de la revista: NEUROLOGIA / OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polisomnografía / Craneosinostosis / Apnea Obstructiva del Sueño / Presión de las Vías Aéreas Positiva Contínua Tipo de estudio: Observational_studies Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Sleep Breath Asunto de la revista: NEUROLOGIA / OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania