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Cardiac tamponade associated with primary myelofibrosis: a case report.
Widodo, Wishnu Aditya; Putra, Teuku Muhammad Haykal; Elfiana, Maria; Khorinal, Eka Widya.
Afiliación
  • Widodo WA; Department of Cardiology and Vascular Medicine, Jakarta Heart Center, Matraman Raya No.23, 13140 Jakarta, Indonesia.
  • Putra TMH; Department of Cardiology and Vascular Medicine, Jakarta Heart Center, Matraman Raya No.23, 13140 Jakarta, Indonesia.
  • Elfiana M; Department of Cardiology and Vascular Medicine, Jakarta Heart Center, Matraman Raya No.23, 13140 Jakarta, Indonesia.
  • Khorinal EW; Department of Hemato-Oncology, Dharmais National Cancer Center, Jakarta, Indonesia.
Eur Heart J Case Rep ; 8(1): ytad630, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38179471
ABSTRACT

Background:

Cardiac tamponade is a life-threatening condition that occurs when an abnormal amount of fluid accumulates in the pericardial sac and impedes the cardiac filling process. Although extremely rare, haematological diseases have the potential to trigger an extramedullary haematopoiesis (EMH) process within the pericardium, resulting in a substantial build-up of pericardial effusion. Case

summary:

We present the case of a 29-year-old male previously diagnosed with primary myelofibrosis (PMF), who presented to the emergency unit with cardiac tamponade. An emergent pericardiocentesis procedure was performed, successfully evacuating 850 mL of haemorrhagic fluid. Over the course of 3 days, a total of 1.5 L of haemorrhagic effusion were drained from the pericardial space. Analysis of the pericardial fluid revealed evidence of haematopoietic activity, suggesting a potential association with the EMH process occurring within the pericardium. Following a 7-day hospitalization, the patient was discharged in stable condition but later experienced the development of constrictive pericarditis.

Discussion:

Haemorrhagic pericardial effusion is a rare occurrence. The majority of cases stems from complications of medical procedures (iatrogenic), malignancies, or side effects of antiplatelet/anticoagulant medications. In patients with PMF, the impaired haematopoietic ability caused by the fibrotic process in the bone marrow compels the body to produce blood components elsewhere, a phenomenon known as EMH. On very rare occasions, EMH can develop in the pericardial space, potentially leading to life-threatening cardiac tamponade. Our patient was successfully managed through pericardial fluid evacuation and drainage but later developed constrictive pericarditis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Eur Heart J Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Risk_factors_studies Idioma: En Revista: Eur Heart J Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Reino Unido