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An overview on viral interference during SARS-CoV-2 pandemic.
Matera, Luigi; Manti, Sara; Petrarca, Laura; Pierangeli, Alessandra; Conti, Maria Giulia; Mancino, Enrica; Leonardi, Salvatore; Midulla, Fabio; Nenna, Raffaella.
Afiliación
  • Matera L; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
  • Manti S; Department of Human and Pediatric Pathology, Pediatric Unit, G. Martino Hospital, University of Messina, Messina, Italy.
  • Petrarca L; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
  • Pierangeli A; Laboratory of Virology, Department of Molecular Medicine, Affiliated to Istituto Pasteur Italia, Sapienza University of Rome, Rome, Italy.
  • Conti MG; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
  • Mancino E; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
  • Leonardi S; Pediatric Respiratory Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
  • Midulla F; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
  • Nenna R; Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Front Pediatr ; 11: 1308105, 2023.
Article en En | MEDLINE | ID: mdl-38178911
ABSTRACT
Respiratory viruses represent the most frequent cause of mortality, morbidity and high healthcare costs for emergency visits and hospitalization in the pediatric age. Respiratory viruses can circulate simultaneously and can potentially infect the same host, determining different types of interactions, the so-called viral interference. The role of viral interference has assumed great importance since December 2019, when the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) came on the scene. The aim of this narrative review is to present our perspective regarding research in respiratory virus interference and discuss recent advances on the topic because, following SARS-CoV-2 restrictions mitigation, we are experimenting the co-circulation of respiratory viruses along with SARS-CoV-2. This scenario is raising many concerns about possible virus-virus interactions, both positive and negative, and the clinical, diagnostic and therapeutic management of these coinfections. Moreover, we cannot rule out that also climatic conditions and social behaviours are involved. Thus, this situation can lead to different population epidemic dynamics, including changes in the age of the targeted population, disease course and severity, highlighting the need for prospective epidemiologic studies and mathematical modelling able to predict the timing and magnitude of epidemics caused by SARS-CoV-2/seasonal respiratory virus interactions in order to adjust better public health interventions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Pediatr Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Pediatr Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza