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Use of percutaneous imaging-guided biopsy for Liver Imaging and Reporting Data System (LI-RADS) observations: A retrospective study from two liver transplant centers.
Furlan, Alessandro; Dasyam, Navya; Buros, Christopher; Thompson, Cole P; Minervini, Marta I; Kierans, Andrea Siobhan.
Afiliación
  • Furlan A; Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA. Electronic address: furlana@upmc.edu.
  • Dasyam N; Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
  • Buros C; Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
  • Thompson CP; Department of Radiology, Mayo Clinic, Phoenix, AZ, USA.
  • Minervini MI; Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Kierans AS; Weill Cornell Medicine, Weill Greenberg Center, 1305 York Avenue, 3rd Floor, New York, NY 10021, USA.
Curr Probl Diagn Radiol ; 53(2): 235-238, 2024.
Article en En | MEDLINE | ID: mdl-38171969
ABSTRACT
Since the adoption of guidelines for the non-invasive imaging diagnosis of hepatocellular carcinoma (HCC), the need for sampling of a lesion in cirrhosis has decreased. We aimed to retrospectively investigate the use of percutaneous imaging-guided biopsy for LI-RADS observations in cirrhosis in two large liver transplant centers. A review of the pathology database in the two Institutions (Institution A, Institution B) was conducted to identify patients that underwent percutaneous imaging-guided biopsy for a liver lesion in the interval time 01/01/2015-12/312020. Liver observations on pre-procedure contrast-enhanced CT or MRI were classified according to LI-RADS v2018. Among the 728 patients who underwent imaging guided biopsy of a liver lesion in Institution A, and among the 749 patients who underwent imaging guided biopsy of a liver lesion in Institution B, respectively 50 (6.8 %) and 16 (2.1 %) were cirrhotic with available pre-procedural contrast-enhanced CT or MRI. A total of 67 lesions were biopsied. 30/67 (45 %) biopsied observations were classified as LR-M. 55/67 (82 %) biopsies were positive for malignancy at histopathology and among them 33 (60 %) were HCC. In conclusion, a small percentage of percutaneous, imaging-guided biopsies for liver lesions are performed in cirrhosis, and more frequently for LR-M observations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Hígado / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudio: Guideline / Observational_studies Límite: Humans Idioma: En Revista: Curr Probl Diagn Radiol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Hígado / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudio: Guideline / Observational_studies Límite: Humans Idioma: En Revista: Curr Probl Diagn Radiol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos