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Binding Interaction Between Lauric Acid and Cluster of Differentiation 36 Underpinned by a Fluorescence- Intensifying Assay.
Tsuzuki, Satoshi; Sugawara, Tatsuya; Manabe, Yuki; Yamasaki, Masayuki; Sasaki, Tsutomu.
Afiliación
  • Tsuzuki S; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University.
  • Sugawara T; Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University.
  • Manabe Y; Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University.
  • Yamasaki M; Department of Food Science and Human Nutrition, Faculty of Agriculture, Ryukoku University.
  • Sasaki T; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University.
J Oleo Sci ; 73(1): 113-119, 2024.
Article en En | MEDLINE | ID: mdl-38171727
ABSTRACT
Cluster of differentiation 36 (CD36) is a scavenger receptor expressed in various vertebrate cells that contains diverse ligands, including long-chain fatty acids. This receptor has recently been suggested as a captor of specific volatile odorants (e.g., aliphatic acetates) in the mammalian nasal epithelium. This study used a fluorescence-intensifying assay to produce the first evidence that lauric acid, an odorous fatty acid, directly binds to CD36. This expansion of the repertoire of volatile ligands supports potential applications for nasal CD36. Our present findings could promote future research aimed at understanding the mechanisms of fatty acid interactions with CD36.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos CD36 / Ácidos Grasos Límite: Animals Idioma: En Revista: J Oleo Sci Asunto de la revista: BIOQUIMICA Año: 2024 Tipo del documento: Article Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos CD36 / Ácidos Grasos Límite: Animals Idioma: En Revista: J Oleo Sci Asunto de la revista: BIOQUIMICA Año: 2024 Tipo del documento: Article Pais de publicación: Japón