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Protein-guided biomimetic nanomaterials: a versatile theranostic nanoplatform for biomedical applications.
Zhang, Da-Gui; Pan, Yu-Jing; Chen, Biao-Qi; Lu, Xiao-Chang; Xu, Qin-Xi; Wang, Pei; Kankala, Ranjith Kumar; Jiang, Ni-Na; Wang, Shi-Bin; Chen, Ai-Zheng.
Afiliación
  • Zhang DG; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Pan YJ; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Chen BQ; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Lu XC; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Xu QX; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Wang P; Jiangxi Provincial Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases, School of Stomatology, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
  • Kankala RK; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Jiang NN; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Wang SB; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
  • Chen AZ; Fujian Provincial Key Laboratory of Biochemical Technology & Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen 361021, China. biaoqi.chen@hqu.edu.cn.
Nanoscale ; 16(4): 1633-1649, 2024 Jan 25.
Article en En | MEDLINE | ID: mdl-38168813
ABSTRACT
Over the years, bioinspired mineralization-based approaches have been applied to synthesize multifunctional organic-inorganic nanocomposites. These nanocomposites can address the growing demands of modern biomedical applications. Proteins, serving as vital biological templates, play a pivotal role in the nucleation and growth processes of various organic-inorganic nanocomposites. Protein-mineralized nanomaterials (PMNMs) have attracted significant interest from researchers due to their facile and convenient preparation, strong physiological activity, stability, impressive biocompatibility, and biodegradability. Nevertheless, few comprehensive reviews have expounded on the progress of these nanomaterials in biomedicine. This article systematically reviews the principles and strategies for constructing nanomaterials using protein-directed biomineralization and biomimetic mineralization techniques. Subsequently, we focus on their recent applications in the biomedical field, encompassing areas such as bioimaging, as well as anti-tumor, anti-bacterial, and anti-inflammatory therapies. Furthermore, we discuss the challenges encountered in practical applications of these materials and explore their potential in future applications. This review aspired to catalyze the continued development of these bioinspired nanomaterials in drug development and clinical diagnosis, ultimately contributing to the fields of precision medicine and translational medicine.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nanocompuestos / Neoplasias Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: Nanoscale Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nanocompuestos / Neoplasias Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: Nanoscale Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido