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Identification of core carcinogenic elements based on the age-standardized mortality rate of lung cancer in Xuanwei Formation coal in China.
Chen, Zailin; Cheng, Xianfeng; Wang, Xingyu; Ni, Shijun; Yu, Qiulian; Hu, Junchun.
Afiliación
  • Chen Z; Engineering Center of Yunnan Education Department for Health Geological Survey and Evaluation, Kunming, 652501, China. 327634884@qq.com.
  • Cheng X; Yunnan Land and Resources Vocational College, Kunming, 652501, China. 327634884@qq.com.
  • Wang X; College of Earth Sciences, Chengdu University of Technology, Chengdu, 610059, China. 327634884@qq.com.
  • Ni S; Engineering Center of Yunnan Education Department for Health Geological Survey and Evaluation, Kunming, 652501, China.
  • Yu Q; Yunnan Land and Resources Vocational College, Kunming, 652501, China.
  • Hu J; College of Earth Sciences, Chengdu University of Technology, Chengdu, 610059, China.
Sci Rep ; 14(1): 232, 2024 01 02.
Article en En | MEDLINE | ID: mdl-38167547
ABSTRACT
In this study, the core carcinogenic elements in Xuanwei Formation coal were identified. Thirty-one samples were collected based on the age-standardized mortality rate (ASMR) of lung cancer; Si, V, Cr, Co, Ni, As, Mo, Cd, Sb, Pb, and rare earth elements and yttrium (REYs) were analyzed and compared; multivariate statistical analyses (CA, PCA, and FDA) were performed; and comprehensive identification was carried out by combining multivariate statistical analyses with toxicology and mineralogy. The final results indicated that (1) the high-concentration Si, Ni, V, Cr, Co, and Cd in coal may have some potential carcinogenic risk. (2) The concentrations of Cr, Ni, As, Mo, Cd, and Pb meet the zoning characteristics of the ASMR, while the Si concentration is not completely consistent. (3) The REY distribution pattern in Longtan Formation coal is lower than that in Xuanwei Formation coal, indicating that the materials of these elements in coal are different. (5) The heatmap divides the sampling sites into two clusters and subtypes in accordance with carcinogenic zoning based on the ASMR. (6) PC1, PC2, and PC3 explain 62.629% of the total variance, identifying Co, Ni, As, Cd, Mo, Cr, and V. (7) Fisher discriminant analysis identifies Ni, Si, Cd, As, and Co based on the discriminant function. (8) Comprehensive identification reveals that Ni is the primary carcinogenic element, followed by Co, Cd, and Si in combination with toxicology. (9) The paragenesis of Si (nanoquartz), Ni, Co, and Cd is an interesting finding. In other words, carcinogenic elements Ni, Co, Cd, and Si and their paragenetic properties should receive more attention.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metales Pesados / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metales Pesados / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido