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MMP-9 gene polymorphisms on cancer risk: an updated systematic review and meta-analysis.
Teng, Zhihai; Wang, Song; Yuan, Hao; Wang, Hu; Li, Jingdong; Chang, Xueliang; Zhang, Yanping; Han, Zhenwei; Wang, Yaxuan.
Afiliación
  • Teng Z; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Wang S; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Yuan H; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Wang H; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Li J; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Chang X; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Zhang Y; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Han Z; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
  • Wang Y; Department of Urology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
Nucleosides Nucleotides Nucleic Acids ; : 1-24, 2024 Jan 03.
Article en En | MEDLINE | ID: mdl-38166515
ABSTRACT
To provide a comprehensive account of the association of MMP-9 gene polymorphisms (rs3918242) with susceptibility to cancer. A literature search for eligible candidate gene studies published before May 27, 2022 was conducted in PubMed, Medline, Google Scholar and Web of Science. Potential sources of heterogeneity were sought out across subgroups and sensitivity analysis. Publication bias were also estimated. Overall, a total of 37 articles with 7616 cases and 8165 controls for rs3918242 gene polymorphisms were enrolled. Our meta-analysis suggests that MMP-9 rs3918242 might be associated with breast cancer and gastric cancer susceptibility, and perhaps reduce the risk of lung cancer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Nucleosides Nucleotides Nucleic Acids Asunto de la revista: BIOQUIMICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Nucleosides Nucleotides Nucleic Acids Asunto de la revista: BIOQUIMICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos