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Utilization of Topical Polysporin and Triamcinolone for the Treatment of Hypergranulation Tissue.
Maynell, Kimberly Brown; West, William; Marek, Jenna; Wright, Benjamin; Bodnar, Michael; Le, Nicole K; Whalen, Kristen; Taylor, Loryn; Troy, Jared; Smith, David; Laun, Jake.
Afiliación
  • Maynell KB; Department of Plastic Surgery, University of South Florida, Tampa, FL 33606, USA.
  • West W; University of South Florida Health Morsani College of Medicine, Tampa, FL 33602, USA.
  • Marek J; University of South Florida Health Morsani College of Medicine, Tampa, FL 33602, USA.
  • Wright B; University of South Florida Health Morsani College of Medicine, Tampa, FL 33602, USA.
  • Bodnar M; University of South Florida Health Morsani College of Medicine, Tampa, FL 33602, USA.
  • Le NK; Department of Plastic Surgery, University of South Florida, Tampa, FL 33606, USA.
  • Whalen K; Department of Plastic Surgery, University of South Florida, Tampa, FL 33606, USA.
  • Taylor L; Department of Plastic Surgery, University of South Florida, Tampa, FL 33606, USA.
  • Troy J; Department of Plastic Surgery, University of South Florida, Tampa, FL 33606, USA.
  • Smith D; Department of Plastic Surgery, University of South Florida, Tampa, FL 33606, USA.
  • Laun J; Department of Plastic Surgery, University of South Florida, Tampa, FL 33606, USA.
J Burn Care Res ; 45(3): 669-674, 2024 05 06.
Article en En | MEDLINE | ID: mdl-38165005
ABSTRACT
Hypergranulation is the abnormal accumulation of granulation tissue in a wound and is commonly seen in burns. It impairs wound healing and can predispose patients to infection. There is no gold standard treatment for hypergranulation tissue, but some options include surgical debridement, chemical cautery with silver nitrate, and topical steroids. Silver nitrate treatment is painful and can lead to scarring, so topical steroid use is on the rise. A retrospective review, between January 1, 2017 and August 30, 2021, at a tertiary burn center was performed to analyze outcomes of hypergranulation tissue after treatment with a topical 50/50 mixture of triamcinolone (Perrigo, Dublin, Ireland) and Polysporin (Johnson & Johnson, New Brunswick, NJ). One hundred and sixteen patients were treated with triamcinolone and Polysporin for hypergranulation tissue, although 24 did not meet inclusion criteria. Eighty-eight out of 92 patients were successfully treated until hypergranulation resolution, while 4/92(4.3%) required silver nitrate or surgery despite the topical cream to achieve resolution. In the 88 patients successfully treated until hypergranulation resolution, 99 areas of hypergranulation were treated. Forty-one of 99 (41.4%) hypergranulation areas resolved within 2 weeks. The average time to hypergranulation resolution was 27.5 ± 2.5 days. We found that a novel 50/50 mixture of triamcinolone and Polysporin topical ointment is an effective and safe treatment for hypergranulation tissue in burn wounds. Further prospective studies are needed to determine its efficacy and safety profile.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quemaduras / Triamcinolona / Tejido de Granulación Tipo de estudio: Observational_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Burn Care Res Asunto de la revista: TRAUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quemaduras / Triamcinolona / Tejido de Granulación Tipo de estudio: Observational_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Burn Care Res Asunto de la revista: TRAUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido