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Solitary Intracranial Plasmacytoma of the Brain Treated With Primary Radiation Therapy.
Kohut-Jackson, Abigail L; Goyal, Sagun D; Carpenter, Danielle H; Shahi, Jeevin.
Afiliación
  • Kohut-Jackson AL; Department of Radiation Oncology, Saint Louis University School of Medicine, St. Louis, USA.
  • Goyal SD; Department of Internal Medicine, Division of Hematology, Oncology, Bone Marrow Transplant and Cellular Therapy, Saint Louis University, St. Louis, USA.
  • Carpenter DH; Department of Pathology, Division of Anatomic Pathology, Saint Louis University, St. Louis, USA.
  • Shahi J; Department of Radiation Oncology, Saint Louis University, St. Louis, USA.
Cureus ; 15(12): e49798, 2023 Dec.
Article en En | MEDLINE | ID: mdl-38161554
ABSTRACT
We present a rare case of a solitary intracranial plasmacytoma of the brain parenchyma in a 49-year-old female who presented with neck pain/headache, paresthesias, and auditory hallucinations. A workup revealed a solitary left parietal lobe brain lesion and a biopsy demonstrated a plasma cell infiltrate consistent with an extramedullary plasmacytoma. A complete workup for multiple myeloma was negative. As opposed to surgical resection and adjuvant radiation therapy (RT), as described in prior case reports in the literature, this patient was managed with definitive local RT alone to 50 Gy in 25 fractions. Six months following primary RT completion, the patient's presenting symptoms completely resolved and follow-up imaging revealed regression of the primary tumor. To our knowledge, this is the first reported case of a solitary extramedullary plasmacytoma of the brain treated with localized definitive RT alone.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos