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Advanced navigation technology enables endobronchial brachytherapy for peripheral lung cancer: An old technique plays a new role.
Li, Yishi; Jiang, Juan; Jiang, Qingfeng; Lu, Wenli; Cui, Haixia; Song, Yanbo; Li, Wencong; Zhang, Tao; Li, Longhao.
Afiliación
  • Li Y; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Jiang J; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Jiang Q; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Lu W; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Cui H; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Song Y; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Li W; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhang T; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Li L; Department of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: llh@hospital.cqmu.edu.cn.
Brachytherapy ; 23(2): 199-206, 2024.
Article en En | MEDLINE | ID: mdl-38161082
ABSTRACT

PURPOSE:

To investigate the feasibility of super-selectively endobronchial brachytherapy in the treatment of peripheral lung cancer guided by advanced navigation technology. METHODS AND MATERIALS Six patients with peripheral lung tumors successfully underwent treatment with super-selectively endobronchial brachytherapy guided by advanced navigation technology following pathway planning and were subsequently followed up to assess survival and treatment-related toxicities.

RESULTS:

The endobronchial applicators were successfully placed inside the tumors of all patients using advanced navigation techniques according to the pretreatment plan, and brachytherapy was delivered at curative doses after evaluation using radiotherapy planning software. None of the patients showed local progression of the treated lesions during the follow-up for a duration ranging from 11 months to 35 months, with a median follow-up time of 23 months. The patient with the longest follow-up, nearly 3 years, exhibited a stable condition. After undergoing endobronchial brachytherapy, patients predominantly experienced localized fibrosis as indicated. No significant alterations in cardiopulmonary function were detected during the follow-up, and no other adverse effects were found.

CONCLUSIONS:

The use of endobronchial brachytherapy for the curative treatment of peripheral lung cancers is feasible. Furthermore, the development of novel bronchial navigation techniques has the potential to broaden the application of endobronchial brachytherapy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Braquiterapia / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Brachytherapy Asunto de la revista: RADIOTERAPIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Braquiterapia / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Brachytherapy Asunto de la revista: RADIOTERAPIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos