Accidental ABO-incompatible pediatric liver transplantation with blood group antigen immune and operational tolerance: a case report with 21 years of follow-up.
Korean J Transplant
; 37(4): 306-309, 2023 Dec 31.
Article
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| MEDLINE
| ID: mdl-38153256
ABSTRACT
Liver transplantation is a critical procedure for patients with end-stage liver disease, but it is often hindered by ABO-incompatibility between the donor and recipient, which can lead to immediate humoral rejection. We present a unique case involving a 10-month-old patient who, by accident, received an ABO-incompatible partial liver transplant from a type A mother without undergoing desensitization. Remarkably, during a 21-year follow-up period, the patient exhibited no signs of humoral or graft rejection, despite nonadherence to medication. This case highlights the possibility of dual tolerance in pediatric ABO-incompatible liver transplantation and provides insights into immune tolerance mechanisms, with implications for enhancing patient care and reducing healthcare costs. Further research is necessary to clarify these mechanisms and to evaluate the long-term durability of tolerance in pediatric transplant recipients.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Korean J Transplant
Año:
2023
Tipo del documento:
Article
Pais de publicación:
Corea del Sur