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Fixed-dose antiretroviral combinations in children living with human immunodeficiency virus type 1 (HIV-1): a systematic review.
Attaianese, Federica; Dalpiaz, Irene; Failla, Martina; Pasquali, Elisa; Galli, Luisa; Chiappini, Elena.
Afiliación
  • Attaianese F; Department of Health Sciences, Section of Paediatrics, University of Florence, Florence, Italy.
  • Dalpiaz I; Department of Health Sciences, Section of Paediatrics, University of Florence, Florence, Italy.
  • Failla M; Department of Health Sciences, Section of Paediatrics, University of Florence, Florence, Italy.
  • Pasquali E; Department of Health Sciences, Section of Paediatrics, University of Florence, Florence, Italy.
  • Galli L; Department of Health Sciences, Section of Paediatrics, University of Florence, Florence, Italy.
  • Chiappini E; Paediatric Infectious Disease Unit, IRCCS Anna Meyer Children's Hospital, Florence, Italy.
J Chemother ; 36(5): 355-369, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38153234
ABSTRACT
Fixed-Dose antiretroviral Combinations (FDCs) are the most used drug regimes in adult patients with human-immunodeficiency virus 1 infection, since they increase adherence to antiretroviral therapy and enable good quality of life. The European AIDS Clinical Society guidelines recommend the use of FDCs in paediatrics. However, the use of FDCs in paediatric population is restricted since studies in children and adolescents are mostly conducted in small sample sizes and are heterogeneous in settings and design. This systematic review aims to summarize the current knowledge about the use of FDCs in paediatric population, highlighting the relevant outcomes regarding efficacy and effectiveness, adherence, safety, and adverse events of these regimens.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 Tipo de estudio: Systematic_reviews Límite: Adolescent / Child / Humans Idioma: En Revista: J Chemother Asunto de la revista: ANTINEOPLASICOS / TERAPIA POR MEDICAMENTOS Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 Tipo de estudio: Systematic_reviews Límite: Adolescent / Child / Humans Idioma: En Revista: J Chemother Asunto de la revista: ANTINEOPLASICOS / TERAPIA POR MEDICAMENTOS Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido