Selected routine laboratory tests in the clinical assessment of patients with obstructive sleep apnea.
Ann Agric Environ Med
; 30(4): 737-742, 2023 Dec 22.
Article
en En
| MEDLINE
| ID: mdl-38153079
ABSTRACT
INTRODUCTION:
Obstructive sleep apnea (OSA) is a chronic disease characterized by repetitive complete or partial occlusion of the upper airways during sleep with respiratory muscle effort, which leads to consecutive apneas and hypopneas. Obstruction of the upper airways during sleep leads to repetitive episodes of disrupted airflow and consequent changes in blood oxygenation, resulting in hypoxaemia and hypercapnia. Intermittent hypoxaemia induces the production of pro-inflammatory factors and promotes metabolic dysregulation and platelet aggregation.OBJECTIVE:
The main aim of this study was to determine differences, if any, in selected standard parameters in routine laboratory tests often used in GP practice between patients with obstructive sleep apnea, without comorbidities, and a well-defined control group with the absence of this syndrome proven in polygraphic examination. MATERIAL ANDMETHODS:
Of the 192 clinically assessed persons with suspected OSA and admitted to the Internal Medicine Department in Lublin, 85 were qualified for the study after application of exclusion criteria. Demographic and health behaviour-related data, medical history regarding sleep habits and cardiovascular disease, were collected from each patient.RESULTS:
Apart from significantly higher MCV and MCH among the cpontrol group, no significant differences were found between patients with obstructive sleep apnea and the control group.CONCLUSIONS:
The results can be useful for the holistic assessment of the health status of patients with newly-diagnosed OSA.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Apnea Obstructiva del Sueño
Límite:
Humans
Idioma:
En
Revista:
Ann Agric Environ Med
Asunto de la revista:
SAUDE AMBIENTAL
Año:
2023
Tipo del documento:
Article
País de afiliación:
Polonia
Pais de publicación:
Polonia