Vaccination time does not influence total anti-SARS-CoV-2 antibodies response.

Pighi, Laura; De Nitto, Simone; Salvagno, Gian Luca; Lippi, Giuseppe

Pighi, Laura; De Nitto, Simone; Salvagno, Gian Luca; Lippi, Giuseppe.

Afiliación

Pighi L; Section of Clinical Biochemistry and School of Medicine, University of Verona, Verona, Italy.
De Nitto S; Section of Clinical Biochemistry and School of Medicine, University of Verona, Verona, Italy.
Salvagno GL; Section of Clinical Biochemistry and School of Medicine, University of Verona, Verona, Italy.
Lippi G; Section of Clinical Biochemistry and School of Medicine, University of Verona, Verona, Italy.

Chronobiol Int ; 41(2): 309-310, 2024 02.

Article en En | MEDLINE | ID: mdl-38148565

ABSTRACT

ABSTRACT

We measured total anti-SARS-CoV-2 receptor-biding domain (RBD) antibodies in 249 healthcare workers (mean age 44 ± 13 years; 151 women), who received the first dose of mRNA-based Comirnaty COVID-19 vaccine at different times of the day. Compared with the reference vaccination time point (i.e. <1000h), vaccine injection at the following times of day elicited a comparable response (all p > 0.05). Under our experimental conditions, we can therefore exclude a possible influence of the timing of primary mRNA-based COVID-19 vaccination on the levels of total anti-SARS-CoV-2 antibodies.

Asunto(s)

COVID-19; Humanos; Femenino; Adulto; Persona de Mediana Edad; Vacunas contra la COVID-19; Ritmo Circadiano; Vacunación; ARN Mensajero

Palabras clave

COVID-19; SARS-CoV-2; Vaccination; antibodies; circadian rhythm

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Límite: Adult / Female / Humans / Middle aged Idioma: En Revista: Chronobiol Int Asunto de la revista: FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido

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