Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09.

Daulagala, Pavithra; Cheng, Samuel M S; Chin, Alex; Luk, Leo L H; Leung, Kathy; Wu, Joseph T; Poon, Leo L M; Peiris, Malik; Yen, Hui-Ling

Daulagala, Pavithra; Cheng, Samuel M S; Chin, Alex; Luk, Leo L H; Leung, Kathy; Wu, Joseph T; Poon, Leo L M; Peiris, Malik; Yen, Hui-Ling.

Emerg Infect Dis ; 30(1): 168-171, 2024 Jan.

Article en En | MEDLINE | ID: mdl-38147510

ABSTRACT

ABSTRACT

We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated.

Asunto(s)

Subtipo H1N1 del Virus de la Influenza A; Subtipo H5N1 del Virus de la Influenza A; Vacunas contra la Influenza; Gripe Aviar; Gripe Humana; Adulto; Animales; Humanos; Neuraminidasa; Anticuerpos Antivirales

Palabras clave

clade 2.3.4.4.b; cross-reactive antibody response; influenza; influenza A(H1N1)pdm09; influenza A(H5N1); neuraminidase inhibition antibody; pandemic risk assessment; respiratory infections; viruses

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunas contra la Influenza / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Subtipo H5N1 del Virus de la Influenza A / Gripe Aviar Límite: Adult / Animals / Humans Idioma: En Revista: Emerg Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

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