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Occupational inhalation exposure during surface disinfection-exposure assessment based on exposure models compared with measurement data.
Anhäuser, Lea; Piorr, Benedikt; Arnone, Mario; Wegscheider, Wolfgang; Gerding, Johannes.
Afiliación
  • Anhäuser L; German Social Accident Insurance Institution for the Health and Welfare Services (BGW), Department for Occupational Medicine, Hazardous Substances and Public Health, Pappelallee 33/35/37, 22089, Hamburg, Germany. Lea.Anhaeuser@bgw-online.de.
  • Piorr B; Federal Institute for Occupational Safety and Health (BAuA), Unit Exposure Assessment Biocides, Friedrich-Henkel-Weg 1-25, 44149, Dortmund, Germany.
  • Arnone M; Institute for Occupational Safety and Health (IFA) of the German Social Accident Insurance (DGUV), Section Exposure Monitoring-MGU, Alte Heerstrasse 111, 53757, Sankt Augustin, Germany.
  • Wegscheider W; German Social Accident Insurance Institution for the Health and Welfare Services (BGW), Department for Occupational Medicine, Hazardous Substances and Public Health, Pappelallee 33/35/37, 22089, Hamburg, Germany.
  • Gerding J; German Social Accident Insurance Institution for the Health and Welfare Services (BGW), Department for Occupational Medicine, Hazardous Substances and Public Health, Pappelallee 33/35/37, 22089, Hamburg, Germany.
J Expo Sci Environ Epidemiol ; 34(2): 345-355, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38145997
ABSTRACT

BACKGROUND:

For healthcare workers, surface disinfections are daily routine tasks. An assessment of the inhalation exposure to hazardous substances, in this case the disinfectant´s active ingredients, is necessary to ensure workers safety. However, deciding which exposure model is best for exposure assessment remains difficult.

OBJECTIVE:

The aim of the study was to evaluate the applicability of different exposure models for disinfection of small surfaces in healthcare settings.

METHODS:

Measurements of the air concentration of active ingredients in disinfectants (ethanol, formaldehyde, glutaraldehyde, hydrogen peroxide, peroxyacetic acid) together with other exposure parameters were recorded in a test chamber. The measurements were performed using personal and stationary air sampling. In addition, exposure modelling was performed using three deterministic models (unsteady 1-zone, ConsExpo and 2-component) and one modifying-factor model (Stoffenmanager®). Their estimates were compared with the measured values using various methods to assess model quality (like accuracy and level of conservatism).

RESULTS:

The deterministic models showed overestimation predominantly in the range of two- to fivefold relative to the measured data and high conservatism for all active ingredients of disinfectants with the exception of ethanol. With Stoffenmanager® an exposure distribution was estimated for ethanol, which was in good accordance with the measured data. IMPACT STATEMENT To date, workplace exposure assessments often involve expensive and time consuming air measurements. Reliable exposure models can be used to assess occupational inhalation exposure to hazardous substances, in this case surface disinfectants. This study describes the applicability of three deterministic and one modifying-factor model for disinfection of small surfaces in healthcare settings, in direct comparison to measurements performed and will facilitate future exposure assessments at these workplaces.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Desinfección / Exposición Profesional / Exposición por Inhalación / Desinfectantes Límite: Humans Idioma: En Revista: J Expo Sci Environ Epidemiol Asunto de la revista: EPIDEMIOLOGIA / SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Desinfección / Exposición Profesional / Exposición por Inhalación / Desinfectantes Límite: Humans Idioma: En Revista: J Expo Sci Environ Epidemiol Asunto de la revista: EPIDEMIOLOGIA / SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos