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The Cross Talk Between Psoriasis, Obesity, and Dyslipidemia: A Meta-Analysis.
Mirghani, Hyder; Altemani, Abdulaziz Talal; Altemani, Sarah Talal; Alhatlani, Juri Ahmad A; Alsulaimani, Naser Mansour I; AlHuraish, Deemah Salem A; Al Mudhi, Ali Hussein A; Ghabban, Waad Jamal R; Alanazi, Ahmed H; Alamrani, Bander Ahmed.
Afiliación
  • Mirghani H; Internal Medicine, Faculty of Medicine, University of Tabuk, Tabuk, SAU.
  • Altemani AT; Dermatology, King Fahad Specialist Hospital, Ministry of Health, Tabuk, SAU.
  • Altemani ST; Dermatology, Faculty of Medicine, University of Tabuk, Tabuk, SAU.
  • Alhatlani JAA; Medicine, Faculty of Medicine, Qassim University, Qassim, SAU.
  • Alsulaimani NMI; Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
  • AlHuraish DSA; Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
  • Al Mudhi AHA; General Practice, Dammam Medical Complex, Ministry of Health, Dammam, SAU.
  • Ghabban WJR; Laboratory, King Khalid Hospital, Ministry of Health, Tabuk, SAU.
  • Alanazi AH; Internal Medicine, King Salman Armed Forces Hospital, Ministry of Defense, Tabuk, SAU.
  • Alamrani BA; Otorhinolaryngology, King Fahad Specialist Hospital, Ministry of Health, Tabuk, SAU.
Cureus ; 15(11): e49253, 2023 Nov.
Article en En | MEDLINE | ID: mdl-38143624
ABSTRACT
Although psoriasis is a multi-organ disease, it is usually managed as a skin disease, ignoring its associated serious comorbidities. This meta-analysis aimed to investigate the relationship between psoriasis, dyslipidemia, and obesity. Two authors independently searched three databases (PubMed, Medical Literature Analysis and Retrieval System Online (MEDLINE), The Cochrane Library, and Google Scholar). The search was set for articles published in the English language during the period from January 2013 to August 2023. The keywords "psoriasis", "hypercholesterolemia", "dyslipidemia", "low-density lipoproteins", "high body mass index", and "obesity", were used. Out of the 145 full texts reviewed, only seven studies fulfilled the inclusion and exclusion criteria (773,761 participants and 196,593 events). Psoriasis was associated with dyslipidemia and obesity (odds ratio (OR)=1.63, 95% CI 1.42-1.88 and OR=1.70, 95% CI 1.43-2.02), respectively, with significant heterogeneity (98% and 97%, respectively). Dyslipidemia and obesity were significant psoriasis comorbidities; a broader approach, viewing psoriasis as a multi-organ disease, is recommended for optimal treatment and outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Cureus Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Cureus Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos