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Molecular markers for malaria genetic epidemiology: progress and pitfalls.
Ruybal-Pesántez, Shazia; McCann, Kirsty; Vibin, Jessy; Siegel, Sasha; Auburn, Sarah; Barry, Alyssa E.
Afiliación
  • Ruybal-Pesántez S; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK; Institute of Microbiology, Universidad San Francisco de Quito, Quito, Ecuador.
  • McCann K; Life Sciences Discipline, Burnet Institute, Melbourne, Victoria, Australia; Centre for Innovation in Infectious Disease and Immunology Research (CIIDIR), Institute for Mental and Physical Health and Clinical Translation (IMPACT) and School of Medicine, Deakin University, Geelong, Victoria, Australia
  • Vibin J; Life Sciences Discipline, Burnet Institute, Melbourne, Victoria, Australia; Centre for Innovation in Infectious Disease and Immunology Research (CIIDIR), Institute for Mental and Physical Health and Clinical Translation (IMPACT) and School of Medicine, Deakin University, Geelong, Victoria, Australia
  • Siegel S; Wellcome Sanger Institute, Hinxton, UK.
  • Auburn S; Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
  • Barry AE; Life Sciences Discipline, Burnet Institute, Melbourne, Victoria, Australia; Centre for Innovation in Infectious Disease and Immunology Research (CIIDIR), Institute for Mental and Physical Health and Clinical Translation (IMPACT) and School of Medicine, Deakin University, Geelong, Victoria, Australia
Trends Parasitol ; 40(2): 147-163, 2024 02.
Article en En | MEDLINE | ID: mdl-38129280
ABSTRACT
Over recent years, progress in molecular markers for genotyping malaria parasites has enabled informative studies of epidemiology and transmission dynamics. Results have highlighted the value of these tools for surveillance to support malaria control and elimination strategies. There are many different types and panels of markers available for malaria parasite genotyping, and for end users, the nuances of these markers with respect to 'use case', resolution, and accuracy, are not well defined. This review clarifies issues surrounding different molecular markers and their application to malaria control and elimination. We describe available marker panels, use cases, implications for different transmission settings, limitations, access, cost, and data accuracy. The information provided can be used as a guide for molecular epidemiology and surveillance of malaria.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malaria Falciparum / Malaria Límite: Humans Idioma: En Revista: Trends Parasitol Asunto de la revista: PARASITOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Ecuador Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malaria Falciparum / Malaria Límite: Humans Idioma: En Revista: Trends Parasitol Asunto de la revista: PARASITOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Ecuador Pais de publicación: Reino Unido