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Post-acute exercise cardiovagal modulation in older male adults with and without type 2 diabetes.
Marôco, João Luís; Arrais, Inês; Silvestre, Tiago; Pinto, Marco; Laranjo, Sérgio; Magalhães, João; Santa-Clara, Helena; Fernhall, Bo; Melo, Xavier.
Afiliación
  • Marôco JL; Integrative Human Physiology Laboratory, Manning College of Nursing & Health Sciences, University of Massachusetts Boston, Boston, MA, USA.
  • Arrais I; Ginásio Clube Português, Research & Development Department, GCP Lab, Lisbon, Portugal.
  • Silvestre T; Centro Interdisciplinar de Estudo da Performance Humana, Faculdade de Motricidade Humana-Universidade de Lisboa, Oeiras, Portugal.
  • Pinto M; Ginásio Clube Português, Research & Development Department, GCP Lab, Lisbon, Portugal.
  • Laranjo S; Centro Interdisciplinar de Estudo da Performance Humana, Faculdade de Motricidade Humana-Universidade de Lisboa, Oeiras, Portugal.
  • Magalhães J; Ginásio Clube Português, Research & Development Department, GCP Lab, Lisbon, Portugal.
  • Santa-Clara H; Faculdade de Ciências da Saúde e do Desporto, Universidade Europeia, Lisbon, Portugal.
  • Fernhall B; Ginásio Clube Português, Research & Development Department, GCP Lab, Lisbon, Portugal.
  • Melo X; Department of Physiology, NOVA Medical School, Faculdade de Ciências Médicas, NMS, FCM, Universidade NOVA de Lisboa, Lisbon, Portugal.
Eur J Appl Physiol ; 124(5): 1475-1486, 2024 May.
Article en En | MEDLINE | ID: mdl-38117338
ABSTRACT

PURPOSE:

We examined heart rate variability (HRV) and baroreflex sensitivity (BRS) disease- and age-related response at 10-and 60-min after an acute high-intensity interval (HIIE) and moderate continuous exercise (MICE) in older adults with and without type 2 diabetes mellitus (T2DM) and healthy young adults.

METHODS:

Twelve older male adults with (57-84 years) and without T2DM (57-76 years) and 12 healthy young male adults (20-40 years) completed an isocaloric acute bout of HIIE, MICE, and a non-exercise condition in a randomized order. Time and Wavelets-derived frequency domain indices of HRV and BRS were obtained in a supine position and offline over 2-min time-bins using Matlab.

RESULTS:

HIIE but not MICE reduced natural logarithm root mean square of successive differences (Ln-RMSSD) (d = - 0.85; 95% CI - 1.15 to - 0.55 ms, p < 0.001), Ln-high-frequency power (d = - 1.60; 95% CI - 2.24 to - 0.97 ms2; p < 0.001), and BRS (d = - 6.32; 95% CI - 9.35 to - 3.29 ms/mmHg, p < 0.001) in adults without T2DM (averaged over young and older adults without T2DM), returning to baseline 60 min into recovery. These indices remained unchanged in older adults with T2DM after HIIE and MICE. Older adults with T2DM had lower resting Ln-RMSSD and BRS than aged-matched controls (Ln-RMSSD, d = - 0.71, 95% CI - 1.16 to - 0.262 ms, p = 0.001; BRS d = - 3.83 ms/mmHg), 95% CI - 6.90 to - 0.76, p = 0.01).

CONCLUSIONS:

Cardiovagal modulation following acute aerobic exercise is intensity-dependent only in adults without T2DM, and appears age-independent. These findings provide evidence of cardiac autonomic impairments in older adults with T2DM at rest and following aerobic exercise.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ejercicio Físico / Barorreflejo / Diabetes Mellitus Tipo 2 / Frecuencia Cardíaca Límite: Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Eur J Appl Physiol Asunto de la revista: FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ejercicio Físico / Barorreflejo / Diabetes Mellitus Tipo 2 / Frecuencia Cardíaca Límite: Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Eur J Appl Physiol Asunto de la revista: FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania