International Water Quality Guidelines for Polycyclic Aromatic Hydrocarbons: Advances to Improve Jurisdictional Uptake of Guidelines Derived Using The Target Lipid Model.
Environ Toxicol Chem
; 43(4): 686-700, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38116959
ABSTRACT
A large number of different of polycyclic aromatic hydrocarbons (PAHs) have been found in environmental media, yet water quality guidelines (WQGs) are only available for a small subset of PAHs, limiting our ability to adequately assess environmental risks from these compounds. The target lipid model (TLM) was published over 20 years ago and has been extensively validated in the literature, but it has still not been widely adopted by jurisdictions to derive WQGs for PAHs. The goal of our study was to better align the methods for deriving TLM-based WQGs with international derivation protocols. This included updating the TLM with rescreened data to identify datapoints by which effect concentrations were estimated rather than measured, modernizing the statistics used to generate the hazard concentration, and testing the applicability of a chronic TLM model rather than using the acute-to-chronic ratio. The results show that the acute TLM model did not deviate substantially from the previous iteration, indicating that the model has reached a point of stability after over 20 years of testing and improvements. Water quality guidelines derived directly from a chronic TLM provided a similar level of protection as previous iterations of the TLM. The major advantage of adopting TLM-derived WQGs is the expanded list of PAH WQGs, which will allow a more fulsome quantification of environmental risks and the ability to apply the model to mixtures. Environ Toxicol Chem 2024;43686-700. © 2023 SETAC.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hidrocarburos Policíclicos Aromáticos
/
Contaminantes Químicos del Agua
Idioma:
En
Revista:
Environ Toxicol Chem
Año:
2024
Tipo del documento:
Article
País de afiliación:
Canadá
Pais de publicación:
Estados Unidos