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A retrospective study of endogenous endophthalmitis-related pyogenic liver abscess: An increasing complication in North Vietnam.
Nguyen, Long Cong; Pham, Thuy Thi-Ngoc; Luu, Diep Thi-Minh; Nguyen, Tinh Nghe; Nguyen, Ngoc Minh; Pham, Hung Ngoc; Doan, Ha Thi-Ngoc; Nguyen, Son Truong; Nguyen, Hieu Van.
Afiliación
  • Nguyen LC; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
  • Pham TT; University of Internal Gastroenterology Department, University of Medicine and Pharmacy, Hanoi National University, Hanoi, Vietnam.
  • Luu DT; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
  • Nguyen TN; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
  • Nguyen NM; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
  • Pham HN; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
  • Doan HT; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
  • Nguyen ST; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
  • Nguyen HV; Gastroenterology and Hepatology Center, Bach Mai Hospital, Hanoi, Vietnam.
SAGE Open Med ; 11: 20503121231218897, 2023.
Article en En | MEDLINE | ID: mdl-38116300
ABSTRACT

Introduction:

Endogenous endophthalmitis-related Klebsiella pyogenic liver abscess is a rare complication of metastatic infection. In most cases, visual acuity results are often impaired, even blind, and even with aggressive treatment with topical antibiotics, the final results are unsatisfactory. The objective of this study is to retrospectively based on medical records to describe clinical features, risk factors, and visual outcomes of patients with endogenous endophthalmitis-related pyogenic liver abscesses.

Methods:

We reported a case series of 12 endogenous endophthalmitis-related pyogenic liver abscess patients from March 2021 to 2023. All cases of endogenous endophthalmitis were diagnosed at admission or during the hospital stay.

Results:

From the medical records of 588 pyogenic liver abscess patients, we found 12 cases of endogenous endophthalmitis with 2.0%. The result showed a mean age of 61.5 ± 12.0 (41-78), diabetes mellitus (7 of 12), right lobe (7 of 12), single abscess (9 of 12), and the mean largest abscess diameter of 5.8 ± 1.7 cm (3.3-9). All patients had ocular symptoms such as eye pain (9 of 12), pus discharge (3 of 12), hypopyon (1 of 12), swollen eyelids (2 of 12), and corneal edema (2 of 12), pyogenic liver abscess before endogenous endophthalmitis (10 of 12), the median interval between endogenous endophthalmitis and pyogenic liver abscess 6.1 ± 1.9 days, ocular symptoms before diagnosis endogenous endophthalmitis 4.4 ± 2.3 days. All affected eyes were injected intravitreously with ceftazidime, amikacin, and vancomycin. Two patients underwent evisceration.

Conclusions:

Endogenous endophthalmitis has permanent morbidity, reducing visual acuity, poor quality of life, and lacks the warning signs, so it is essential for early detection of symptoms and referral to ophthalmologists.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: SAGE Open Med Año: 2023 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: SAGE Open Med Año: 2023 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido