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Post-tonsillectomy bleeding rate decreases with limitation in maximum post-operative ibuprofen dosage: A quality improvement study.
Rosi-Schumacher, Mattie; Sharma, Jyoti; Clausen, Sean; Favre, Nicole; Powers, Kristina; Carr, Michele.
Afiliación
  • Rosi-Schumacher M; Department of Otolaryngology-Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY 14209, United States of America.
  • Sharma J; Department of Otolaryngology-Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY 14209, United States of America.
  • Clausen S; Department of Otolaryngology-Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY 14209, United States of America.
  • Favre N; Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14209, United States of America.
  • Powers K; Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14209, United States of America.
  • Carr M; Department of Otolaryngology-Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY 14209, United States of America. Electronic address: mcarr@buffalo.edu.
Am J Otolaryngol ; 45(2): 104197, 2024.
Article en En | MEDLINE | ID: mdl-38113775
ABSTRACT

OBJECTIVE:

The objective of this study is to investigate the effect of a reduction in the prescribed post-operative ibuprofen dosage on frequency of post-tonsillectomy bleeding.

METHODS:

A quality improvement study was conducted at a single tertiary care pediatric hospital with patients weighing >40 kg undergoing tonsillectomy. The intervention was limiting the post-operative ibuprofen dosage to a maximum of 400 mg per dose. Data was collected on all patients returning to the hospital with bleeding after tonsillectomy. The primary outcome was the rate of post-tonsillectomy bleeding. Statistical analysis was conducted using nonparametric comparisons and a run chart.

RESULTS:

A total of 199 tonsillectomy patients >40 kg were included in the study. There were 119 (59.8 %) females and 80 (40.2 %) males total. The pre-intervention group had a total of 56 patients while the post-intervention group had a total of 143 patients. There was no statistical difference in age, weight, or sex between the pre- and post-intervention groups (p > .05). The post-tonsillectomy hemorrhage rate was 11/56 (19.6 %) before the intervention, and 11/143 (7.7 %) after the intervention (p = .016). Children who experienced a bleeding event were significantly older (mean 15.9 years, 95 % CI 14.5-17.3) than those who did not (13.5 years, 95 % CI 12.9-14.1; p = .011). The run chart revealed that the intervention resulted in a nonrandom decrease in rate of post-tonsillectomy bleeding.

CONCLUSIONS:

Post-tonsillectomy bleeding rate decreased with a ceiling post-operative ibuprofen dose of 400 mg/dose in this quality improvement study. Further research is warranted.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonsilectomía / Ibuprofeno Límite: Child / Female / Humans / Male Idioma: En Revista: Am J Otolaryngol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonsilectomía / Ibuprofeno Límite: Child / Female / Humans / Male Idioma: En Revista: Am J Otolaryngol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos