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Evaluation of Proximal Femoral Bone Mineral Density in Cementless Total Hip Arthroplasty: A 3-Arm Prospective Randomized Controlled Trial.
Hooper, Gary; Thompson, Deirdre; Frampton, Christopher; Lash, Nicholas; Sharr, Jonathan; Fulker, David; Gilchrist, Nigel.
Afiliación
  • Hooper G; CGM Research Trust, Christchurch, South Island, New Zealand.
  • Thompson D; Department of Orthopaedic Surgery and Musculoskeletal Medicine, University of Otago, Christchurch, South Island, New Zealand.
  • Frampton C; CGM Research Trust, Christchurch, South Island, New Zealand.
  • Lash N; Department of Medicine, University of Otago, Christchurch, South Island, New Zealand.
  • Sharr J; Department of Orthopaedic Surgery and Musculoskeletal Medicine, University of Otago, Christchurch, South Island, New Zealand.
  • Fulker D; Department of Orthopaedic Surgery and Musculoskeletal Medicine, University of Otago, Christchurch, South Island, New Zealand.
  • Gilchrist N; Stryker Australia, St Leonards, Sydney, Australia.
J Bone Joint Surg Am ; 106(6): 508-516, 2024 Mar 20.
Article en En | MEDLINE | ID: mdl-38113306
ABSTRACT

BACKGROUND:

Femoral stem design affects periprosthetic bone mineral density (BMD), which may impact long-term survival of cementless implants in total hip arthroplasty (THA). The aim of this study was to examine proximal femoral BMD in 3 morphologically different uncemented femoral stem designs to investigate whether any particular design resulted in better preservation of BMD.

METHODS:

A total of 119 patients were randomized to receive a proximally coated collarless dual-taper wedge stem, a proximally coated collarless anatomic stem, or a fully coated collarless triple-taper stem. All surgeries were performed via the posterior approach, with mobilization on the day of surgery. Dual x-ray absorptiometry scans (Lunar iDXA, GE Healthcare) assessed BMD across the 7 Gruen zones preoperatively and at 6 weeks and 2 years postoperatively; if available, the native contralateral femur was also assessed as a control. Patient-reported outcomes of pain, function, and health were also assessed at these follow-ups.

RESULTS:

Averaged across all stems, BMD increased in zones 1 (2.5%), 2 (17.1%), 3 (13.0%), 5 (10%), and 6 (17.9%) at 2 years. Greater preservation of BMD was measured on the lateral cortex (zone 2) for both the dual-taper wedge and anatomic stems (p = 0.019). The dual-taper wedge stem also demonstrated preservation of BMD in the medial calcar (zone 7), while the anatomic and triple-taper stems declined in this region; however, the difference did not reach significance (p = 0.059). Averaged across all stems, BMD decreased in the mid-diaphysis region, distal to the stem tip (zone 4). All stems performed similarly at the time of final follow-up with respect to the patient-reported outcomes.

CONCLUSIONS:

This study demonstrated maintenance of femoral BMD after use of 3 different cementless femoral stem designs, with all achieving excellent improvements in patient-reported outcomes. The stems designed to load the proximal metaphyseal region resulted in higher BMD in that region. No significant stress-shielding was observed; however, longer follow-up is required to elucidate the impact of this finding on implant survivorship. LEVEL OF EVIDENCE Therapeutic Level I . See Instructions for Authors for a complete description of levels of evidence.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artroplastia de Reemplazo de Cadera / Prótesis de Cadera Límite: Humans Idioma: En Revista: J Bone Joint Surg Am Año: 2024 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artroplastia de Reemplazo de Cadera / Prótesis de Cadera Límite: Humans Idioma: En Revista: J Bone Joint Surg Am Año: 2024 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Estados Unidos