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Hemoglobin A1c and Reoperation After Surgery for Stress Incontinence or Prolapse.
Bachar, Austin; Wang, Xi; Herzog, Kiersten; Sahil, Suman; Cheng, An-Lin; Ohene-Agyei, Jada A; Shepherd, Jonathan P; Sutkin, Gary.
Afiliación
  • Bachar A; From the University of Missouri Kansas City School of Medicine, Kansas City, MO.
  • Wang X; From the University of Missouri Kansas City School of Medicine, Kansas City, MO.
  • Herzog K; From the University of Missouri Kansas City School of Medicine, Kansas City, MO.
  • Sahil S; From the University of Missouri Kansas City School of Medicine, Kansas City, MO.
  • Cheng AL; From the University of Missouri Kansas City School of Medicine, Kansas City, MO.
  • Ohene-Agyei JA; From the University of Missouri Kansas City School of Medicine, Kansas City, MO.
  • Shepherd JP; University of Connecticut Health Center, Farmington, CT.
  • Sutkin G; From the University of Missouri Kansas City School of Medicine, Kansas City, MO.
Article en En | MEDLINE | ID: mdl-38113124
ABSTRACT
IMPORTANCE Few studies compare the link between hemogobin A1c (HbA1c) and urogynecologic surgical complications.

OBJECTIVE:

The objective of this study was to determine the association between HbA1c and reoperation in women undergoing surgery for stress urinary incontinence (SUI) or pelvic organ prolapse (POP). STUDY

DESIGN:

We performed 2 separate retrospective cohort analyses using Cerner's HealthFacts Database (750 hospitals; 519,000,000 patient encounters from January 1, 2010, to November 30, 2018). We included women undergoing surgery for (1) SUI or (2) apical POP by International Classification of Diseases coding who had HbA1c at the initial procedure. Each analysis compared those undergoing reoperation for complications or recurrence and those who did not. Multivariable logistic regression assessed the association between reoperation and HbA1c both as a continuous variable and comparing the commonly accepted cutoff ≥8.

RESULTS:

Of 30,180 SUI surgical procedures and 26,389 POP surgical procedures, 1,625 (5.4%) and 805 (3.1%) had HbA1c. Median (interquartile range) HbA1c in grams per deciliter was similar by reoperation status (SUI 6.0 [5.6-6.8] vs 6.1 [5.6-6.9], P = 0.35; POP 6.2 [5.6-6.6] vs 6.1 [5.7-6.8], P = 0.60). Reoperation was also similar using the HbA1c ≥8% cutoff (SUI 6.9% vs 7.4%, P = 0.79; POP 6.3% vs 5.4%, P = 0.77). On multivariate analysis, HbA1c value was not a significant predictor of reoperation either as a continuous (SUI odds ratio [OR] = 0.966, 95% CI = 0.833-1.119; POP OR = 1.040, 95% CI = 0.801-1.350) or dichotomous variable ≥8 (SUI OR = 0.767, 95% CI = 0.407-1.446; POP OR = 0.988, 95% CI = 0.331-2.951). Mean follow-up was 4.28-5.13 years.

CONCLUSION:

Although other studies have shown a link between diabetes and complications, we were unable to show an association between HbA1c values and rates of reoperation.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Urogynecology (Phila) Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Urogynecology (Phila) Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos