Serological evidence of virus infection in Eidolon helvum fruit bats: implications for bushmeat consumption in Nigeria.
Front Public Health
; 11: 1283113, 2023.
Article
en En
| MEDLINE
| ID: mdl-38106901
ABSTRACT
Introduction:
The Eidolon helvum fruit bat is one of the most widely distributed fruit bats in Africa and known to be a reservoir for several pathogenic viruses that can cause disease in animals and humans. To assess the risk of zoonotic spillover, we conducted a serological survey of 304 serum samples from E. helvum bats that were captured for human consumption in Makurdi, Nigeria.Methods:
Using pseudotyped viruses, we screened 304 serum samples for neutralizing antibodies against viruses from the Coronaviridae, Filoviridae, Orthomyxoviridae and Paramyxoviridae families.Results:
We report the presence of neutralizing antibodies against henipavirus lineage GH-M74a virus (odds ratio 6.23; p < 0.001), Nipah virus (odds ratio 4.04; p = 0.00031), bat influenza H17N10 virus (odds ratio 7.25; p < 0.001) and no significant association with Ebola virus (odds ratio 0.56; p = 0.375) in this bat cohort.Conclusion:
The data suggest a potential risk of zoonotic spillover including the possible circulation of highly pathogenic viruses in E. helvum populations. These findings highlight the importance of maintaining sero-surveillance of E. helvum, and the necessity for further, more comprehensive investigations to monitor changes in virus prevalence, distribution over time, and across different geographic locations.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Virosis
/
Quirópteros
Límite:
Animals
/
Humans
País/Región como asunto:
Africa
Idioma:
En
Revista:
Front Public Health
Año:
2023
Tipo del documento:
Article
País de afiliación:
Reino Unido
Pais de publicación:
Suiza