Your browser doesn't support javascript.
loading
An amplicon-based Illumina and nanopore sequencing workflow for Chikungunya virus West Africa genotype.
Dieng, Idrissa; Ndiaye, Mignane; Kane, Mouhamed; Balde, Diamilatou; Mbanne, Maimouna; Diop, Seynabou Mbaye Ba Souna; Sankhe, Safietou; Dia, Moussa; Dieng, Madeleine; Doukanda, Serge Freddy Moukaha; Faye, Ousmane; Sall, Amadou Alpha; Dia, Ndongo; Fall, Gamou; Faye, Oumar; Diagne, Moussa Moise.
Afiliación
  • Dieng I; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Ndiaye M; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Kane M; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Balde D; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Mbanne M; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Diop SMBS; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Sankhe S; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Dia M; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Dieng M; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Doukanda SFM; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Faye O; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Sall AA; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Dia N; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Fall G; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Faye O; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
  • Diagne MM; Virology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
medRxiv ; 2023 Dec 09.
Article en En | MEDLINE | ID: mdl-38106224
ABSTRACT
The Chikungunya virus, a global arbovirus, is currently causing a major outbreak in the Western African region, with the highest cases reported in Senegal and Burkina Faso. Recent molecular evolution analyses reveal that the strain responsible for the epidemic belongs to the West African genotype, with new mutations potentially impacting viral replication, antigenicity, and host adaptation. Real-time genomic monitoring is needed to track the virus's spread in new regions. A scalable West African genotype amplicon-based Whole Genome Sequencing for multiple Next Generation Sequencing platforms has been developed to support genomic investigations and identify epidemiological links during the virus's ongoing spread. This technology will help identify potential threats and support real-time genomic investigations in the ongoing spread of the virus.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: MedRxiv Año: 2023 Tipo del documento: Article País de afiliación: Senegal Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: MedRxiv Año: 2023 Tipo del documento: Article País de afiliación: Senegal Pais de publicación: Estados Unidos