Your browser doesn't support javascript.
loading
Experimental infection of aquatic bird bornavirus 1 (ABBV-1) in Canada geese (Branta canadensis).
Ampuero, Fernanda; Leacy, Alexander; Pham, Phuc H; Che, Sunoh; Tuling, Jaime; El-Khoury, Antonius; Nagy, Eva; Jardine, Claire; Delnatte, Pauline; Lillie, Brandon; Susta, Leonardo.
Afiliación
  • Ampuero F; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Leacy A; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Pham PH; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Che S; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Tuling J; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • El-Khoury A; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Nagy E; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Jardine C; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Delnatte P; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Lillie B; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada.
  • Susta L; University of Guelph, Pathobiology, Guelph, N1G2W1, Canada. Electronic address: lsusta@uoguelph.ca.
Vet Microbiol ; 288: 109946, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38103394
ABSTRACT
Aquatic bird bornavirus 1 (ABBV-1) has a high prevalence of infection in certain North American populations of Canada geese (Branta canadensis), suggesting a possible role of these birds as an ABBV-1 reservoir. The goal of this study was to evaluate the ability of Canada geese to become experimentally infected with ABBV-1, develop lesions, and transmit the virus to conspecifics. One-week-old Canada geese (n, 65) were inoculated with ABBV-1 through the intramuscular (IM) or cloacal (CL) routes, with the control group receiving carrier only. An additional 6 geese were added to each group to test horizontal transmission (sentinel birds). Geese were monitored daily, and selected birds were euthanized at 1, 8, and 15-weeks post infection (wpi) to assess virus replication in tissues and lesion development. At 15 wpi, over 70% of IM birds were infected, while the CL route yielded only 1 infected goose. Of the infected IM geese, 26% developed encephalitis and/or myelitis after 8 wpi. No clinical signs were observed, and no sentinel birds became infected in any group. Only 1 oropharyngeal swab (IM group) tested positive for ABBV-1 RNA, while the water from the enclosures was consistently negative for virus RNA. This study documents successful experimental infection of Canada geese with ABBV-1, with findings comparable to what is described in infection trials with other waterfowl species. However, minimal shedding and lack of environmental dispersal indicate that Canada geese have little potential to disseminate the virus among wild waterfowl, and that other species could be better suited to act as chronic ABBV-1 shedders in the wild.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de las Aves / Bornaviridae Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: Vet Microbiol Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de las Aves / Bornaviridae Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: Vet Microbiol Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Países Bajos