Tear clearance rate in dogs: Measurement using anterior segment optical coherence tomography.
Vet Med Sci
; 10(1): e1334, 2024 01.
Article
en En
| MEDLINE
| ID: mdl-38100149
ABSTRACT
OBJECTIVE:
The tear clearance rate (TCR), determined using anterior segment optical coherence tomography (AS-OCT) images, and its correlation with ocular surface parameters, including blink rate, Schirmer tear test-1 (STT-1) and tear film breakup time (TFBUT), were evaluated. ANIMALS STUDIED Left eyes of 20 client-owned dogs with no ocular disease symptoms. PROCEDURES The tear meniscus height (TMH) was evaluated using AS-OCT images before the instillation of 5 µL saline (TMHbase ), immediately post-instillation (TMH0 ), 30-s post-instillation (TMH0.5 ) and at 1 min intervals for 5 min post-instillation (TMH1 , TMH2 , TMH3 , TMH4 and TMH5 ). The TCR was calculated using the formula [(TMH0 - TMH0.5 )/TMH0 ]×100 (%). The eyes were classified into two groups with the median 'High TMHbase ' (n = 10) and 'Low TMHbase ' (n = 10). Eyes with STT-1 values ≥15 mm/min and TFBUT ≥ 12 s were assigned to the 'Satisfied' subgroup, whereas eyes not satisfying these criteria were assigned to the 'Not satisfied' subgroup.RESULTS:
TMH0 was higher than TMH0.5 (p = 0.02), wherein TMH0.5 to TMH5 did not differ significantly. The TCR and blink rate were negatively correlated (p = 0.02). The 'Not satisfied' subgroup in the low TMHbase group had a lower TCR (p = 0.02) and higher blink rate (p = 0.04) than the 'Satisfied' subgroup.CONCLUSIONS:
TCR can be evaluated using AS-OCT in dogs. Eyes with a lower TCR blink more frequently. TMH merits studying to understand ocular surface health.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndromes de Ojo Seco
/
Enfermedades de los Perros
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Vet Med Sci
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Reino Unido