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Current Characteristics of Herbal Medicine Interventions for Cancer on Clinical Databases: A Cross-Sectional Study.
Youn, Bo-Young; Kim, Ji-Hyun; Jo, Yong-Kyu; Yoon, Sanghoon; Im, Ji-Yeong; Kim, Hyo-Jung; Lee, Jae-Dong; Ko, Seong-Gyu.
Afiliación
  • Youn BY; Hwasung Medi-Science University, Hwaseong-si, Gyeonggi-do, South Korea.
  • Kim JH; Kyung Hee University, Seoul, Republic of Korea.
  • Jo YK; Kyung Hee University, Seoul, Republic of Korea.
  • Yoon S; Kyung Hee University, Seoul, Republic of Korea.
  • Im JY; Kyung Hee University, Seoul, Republic of Korea.
  • Kim HJ; Kyung Hee University, Seoul, Republic of Korea.
  • Lee JD; Kyung Hee University, Seoul, Republic of Korea.
  • Ko SG; Kyung Hee University, Seoul, Republic of Korea.
Integr Cancer Ther ; 22: 15347354231218255, 2023.
Article en En | MEDLINE | ID: mdl-38099482
ABSTRACT

BACKGROUND:

The utilization of herbal medicine has been noteworthy for treating cancer; however, there is not enough information regarding the characteristics of clinical trials of herbal medicine interventions. This study aimed to evaluate the characteristic of registered trials using herbal medicine interventions for cancer.

METHODS:

A cross-sectional study was performed via the website ClinicalTrials.gov, ISRCTN registry, Chinese clinical trial registry, and international clinical trials registry platform to gather associated registered clinical trials using an advanced search with the developed keyword strategy as of March 26, 2023. All obtainable information from the trials was collected without any restrictions to conduct a comprehensive review.

RESULTS:

A total of 169 registered trials were included for evaluation. Of all trials, 102 trials were eligible for this study. Countries from Asia registered the most trials (62.75%), and hospitals sponsored most of the trials (42.16%). Randomized, Phase 2, interventional trials were dominant, and approximately 64.71% of the trials anticipated recruiting less than 100 participants. More than half of the trials were from 2016 to 2023 (53.92%). While 45 trials were completed, only 16 trials had results for further analysis. According to the completed results, the types of herbal medicines from the trials mainly focused on lung, breast, and colorectal cancer.

CONCLUSION:

This study is the first to explore the characteristics of clinical trials of herbal medicine for cancer registered in large clinical databases. The acquired trials had relatively informative data; however, better-designed trials may be needed for health professionals to consider herbal medicine as an option when treating cancer patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plantas Medicinales / Medicamentos Herbarios Chinos / Neoplasias Límite: Humans Idioma: En Revista: Integr Cancer Ther Asunto de la revista: NEOPLASIAS / TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plantas Medicinales / Medicamentos Herbarios Chinos / Neoplasias Límite: Humans Idioma: En Revista: Integr Cancer Ther Asunto de la revista: NEOPLASIAS / TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Estados Unidos