Treatment of post-burn pruritus - A systematic review and meta-analysis.
Burns
; 50(2): 293-301, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38097439
ABSTRACT
BACKGROUND:
Post-burn pruritus is one of the most common complaints reported by patients with limited evidence for a gold-standard treatment.OBJECTIVE:
To review the literature and assess the efficacy of various interventions in treating post-burn pruritus.METHODS:
PubMed, MEDLINE, CINAHL, Web of Sciences, Ovid Databases, and ClinicalTrials.Gov were searched. The articles were scored by two assessors for inclusion with a third independent assessor resolving conflicting scores.RESULTS:
The present systematic review and meta-analysis synthesised findings from a total of nine studies, representing a pool of 323 patients. The standardized mean effect size for the various categories of interventions was naltrexone at 1.47 (95 % CI of 0.75-2.20, p < 0.0000), coverings at 0.94 (95 % CI of 0.40-1.48, p = 0.006), topical ozonated oil at 2.64 (95 % CI of 1.94-3.34, p < 0.00001), lasers at 2.34 (95 % CI of 1.60-3.09, p < 0.00001), current stimulation at 1.03 (95 % CI of -0.04 to 2.10, p = 0.06), and lemon balm tea at 0.54 (95% CI of 0.12-0.96, p = 0.01).CONCLUSIONS:
Current evidence suggests that current modalities have a statistically significant, but not clinically significant, reduction in pruritus. This review highlights the limited quality of evidence in the literature and the poor quality of reporting among excluded studies.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Prurito
/
Quemaduras
/
Naltrexona
Tipo de estudio:
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Burns
Asunto de la revista:
TRAUMATOLOGIA
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Países Bajos