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Diagnostic value of serum autotaxin level in colorectal cancer.
Baspinar, Abdurrahman; Özkan, Didem; Tokgöz, Serhat; Özkardes, Alper Bilal; Kaya, Ismail Oskay.
Afiliación
  • Baspinar A; Department of General Surgery, Ankara Training and Research Hospital, University of Health Science, Ankara, 06230, Turkey.
  • Özkan D; Department of Microbiology, Etlik City Hospital, University of Health Science, Ankara, 06170, Turkey.
  • Tokgöz S; Department of General Surgery, Etlik City Hospital, University of Health Science, Ankara, 06170, Turkey.
  • Özkardes AB; Department of General Surgery, Ankara Hospital, Lokman Hekim University, Ankara, 06510, Turkey.
  • Kaya IO; Department of General Surgery, Etlik City Hospital, University of Health Science, Ankara, 06170, Turkey.
Biomark Med ; 17(19): 787-798, 2023 10.
Article en En | MEDLINE | ID: mdl-38095984
What is this summary about? Here, we summarize the results from 'The diagnostic value of serum autotaxin level in colorectal cancer' study, published in Biomarkers in Medicine. This study examined a biomarker that could enable the early diagnosis of colorectal cancer. Autotaxin (ATX) plays a key role in inflammatory and neoplastic processes. In our study, serum ATX levels were measured in patients with colorectal cancer. What are the results? Serum ATX levels were higher in patients with colorectal cancer than in healthy volunteers. ATX levels were not associated with tumor stage. However, ATX levels were lower in mucinous adenocarcinomas. The ATX levels were higher in females than males. Although our study sample was small, we observed that ATX was more sensitive and specific than carcinoembryonic antigen in detecting colorectal cancer. What do these results mean? Serum ATX levels are promising biomarkers for colorectal cancer diagnosis and patient surveillance.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Hidrolasas Diéster Fosfóricas Límite: Humans Idioma: En Revista: Biomark Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Hidrolasas Diéster Fosfóricas Límite: Humans Idioma: En Revista: Biomark Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido