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The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes.
Raguseo, Federica; Wang, Yiran; Li, Jessica; Petric Howe, Marija; Balendra, Rubika; Huyghebaert, Anouk; Vadukul, Devkee M; Tanase, Diana A; Maher, Thomas E; Malouf, Layla; Rubio-Sánchez, Roger; Aprile, Francesco A; Elani, Yuval; Patani, Rickie; Di Michele, Lorenzo; Di Antonio, Marco.
Afiliación
  • Raguseo F; Imperial College London, Department of Chemistry, Molecular Sciences Research Hub, 82 Wood Lane, London, W12 0BZ, UK.
  • Wang Y; University of Cambridge, Department of Chemical Engineering and Biotechnology, Philippa Fawcett Drive, Cambridge, CB3 0AS, UK.
  • Li J; Imperial College London, Institute of Chemical Biology, Molecular Sciences Research Hub, 82 Wood Lane, London, W12 0BZ, UK.
  • Petric Howe M; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Balendra R; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
  • Huyghebaert A; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Vadukul DM; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
  • Tanase DA; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Maher TE; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
  • Malouf L; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  • Rubio-Sánchez R; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
  • Aprile FA; Imperial College London, Department of Chemistry, Molecular Sciences Research Hub, 82 Wood Lane, London, W12 0BZ, UK.
  • Elani Y; Imperial College London, Institute of Chemical Biology, Molecular Sciences Research Hub, 82 Wood Lane, London, W12 0BZ, UK.
  • Patani R; Imperial College London, Department of Chemistry, Molecular Sciences Research Hub, 82 Wood Lane, London, W12 0BZ, UK.
  • Di Michele L; Imperial College London, Department of Chemistry, Molecular Sciences Research Hub, 82 Wood Lane, London, W12 0BZ, UK.
  • Di Antonio M; University of Cambridge, Department of Chemical Engineering and Biotechnology, Philippa Fawcett Drive, Cambridge, CB3 0AS, UK.
Nat Commun ; 14(1): 8272, 2023 Dec 13.
Article en En | MEDLINE | ID: mdl-38092738

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: G-Cuádruplex / Demencia Frontotemporal / Esclerosis Amiotrófica Lateral Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: G-Cuádruplex / Demencia Frontotemporal / Esclerosis Amiotrófica Lateral Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido