Live-cell imaging Unveils stimulus-specific dynamics of Nrf2 activation in UV-exposed melanoma cells: Implications for antioxidant compound screening.

Htut, Nilar Win; Onkoksoong, Tasanee; Saelim, Malinee; Kueanjinda, Patipark; Sampattavanich, Somponnat; Panich, Uraiwan

Htut, Nilar Win; Onkoksoong, Tasanee; Saelim, Malinee; Kueanjinda, Patipark; Sampattavanich, Somponnat; Panich, Uraiwan.

Afiliación

Htut NW; Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand; University of Medicine 2, Yangon, Khaymar Thi Rd, Yangon, Myanmar.
Onkoksoong T; Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Saelim M; Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Kueanjinda P; Center of Excellence in Immunology and Immune-mediated Diseases, Division of Immunology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Sampattavanich S; Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand; Siriraj Center of Research Excellence (SiCORE) for Systems Pharmacology, Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Panich U; Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand. Electronic address: uraiwan.pan@mahidol.ac.th.

Free Radic Biol Med ; 211: 1-11, 2024 02 01.

Article en En | MEDLINE | ID: mdl-38092271

Asunto(s)

Antioxidantes; Melanoma; Humanos; Antioxidantes/farmacología; Factor 2 Relacionado con NF-E2/genética; Factor 2 Relacionado con NF-E2/metabolismo; Melanoma/genética; Elementos de Respuesta Antioxidante/genética; Estrés Oxidativo

Palabras clave

Living cell-based biosensor; Nuclear factor erythroid 2-related factor 2 (Nrf2); Ultraviolet (UV) radiation; phytochemicals

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Melanoma / Antioxidantes Límite: Humans Idioma: En Revista: Free Radic Biol Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: Myanmar Pais de publicación: Estados Unidos

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