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Trends of Costs and Admission Rates Among Patients Admitted With Autoimmune Hepatitis: Analysis of US Hospitals Using the NIS Database.
Lee, David U; Schuster, Kimberly; Bahadur, Aneesh; Schellhammer, Sophie; Ponder, Reid; Mitchell-Sparke, Emma; Fan, Gregory H; Lee, Ki J; Chou, Harrison; Lominadze, Zurabi.
Afiliación
  • Lee DU; Division of Gastroenterology and Hepatology, University of Maryland, 22 S. Greene St, Baltimore, MD, 21201, USA.
  • Schuster K; Department of Medicine, Tufts University School of Medicine, Washington St, Boston, MA, 02111, USA.
  • Bahadur A; Department of Medicine, Tufts University School of Medicine, Washington St, Boston, MA, 02111, USA.
  • Schellhammer S; Vanderbilt University School of Medicine, 21st Ave S, Nashville, TN, USA.
  • Ponder R; Department of Medicine, Tufts University School of Medicine, Washington St, Boston, MA, 02111, USA.
  • Mitchell-Sparke E; Department of Medicine, Tufts University School of Medicine, Washington St, Boston, MA, 02111, USA.
  • Fan GH; Department of Medicine, Tufts University School of Medicine, Washington St, Boston, MA, 02111, USA.
  • Lee KJ; Department of Medicine, Tufts University School of Medicine, Washington St, Boston, MA, 02111, USA.
  • Chou H; Department of Medicine, Tufts University School of Medicine, Washington St, Boston, MA, 02111, USA.
  • Lominadze Z; Division of Gastroenterology and Hepatology, University of Maryland, 22 S. Greene St, Baltimore, MD, 21201, USA.
J Clin Exp Hepatol ; 14(1): 101279, 2024.
Article en En | MEDLINE | ID: mdl-38076380
ABSTRACT
Background and

aim:

Autoimmune hepatitis (AIH) is a prominent cause of chronic liver disease in the United States. This study aims to characterize the incidence, mortality, and cost implications of this condition using a national database.

Method:

The 2016-2019 National Inpatient Sample was used to select patients with AIH. After adjusting for inflation, weighted charge data were used to calculate the admission costs using charge-to-cost ratios. Demographic, socioeconomic status, and comorbidity values were used to build strata to characterize admission incidence, mortality data and aggregate and per-capita cost values. Furthermore, additional sensitivity analysis was performed using a stratified set of patients with AIH as one of the top 10 diagnosis (AIH-specific subsample). Multinomial regression curves were graphed and assessed to derive goodness-of-fit for each trend. R2 and P-values were calculated.

Results:

From 2016 to 2019, the total admissions related to AIH were approximately 20,984, 21,905, 22,055, and 22,680 cases, respectively (R2 0.93, P-value 0.03). AIH-related hospitalization aggregate costs came to $338.18, $369.17, $355.98, and $387.25 million dollars (R2 0.75, P-value 0.17). Significant admission growth was seen in the Southern region (R2 0.91, P-value 0.05). Most notably, increasing trends in total admissions were found across older age, those of White and Hispanic descent, and those with comorbidities. On the other hand, the AIH-specific subsample illustrated decreasing trends in admissions across demographics (i.e., age, gender, and race) and comorbidities; however, those with hepatic complications saw a rise in the admission trends (cirrhosis - R2 0.98, P-value 0.009; multiple liver complications - R2 0.95, P-value 0.03).

Conclusion:

Among AIH-specific admissions, there was a decreasing trend overall; however, there was an exceptional increase in the admissions among those with hepatic complications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Exp Hepatol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Exp Hepatol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: India