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Conjugates of amiridine and thiouracil derivatives as effective inhibitors of butyrylcholinesterase with the potential to block ß-amyloid aggregation.
Khudina, Olga G; Grishchenko, Maria V; Makhaeva, Galina F; Kovaleva, Nadezhda V; Boltneva, Natalia P; Rudakova, Elena V; Lushchekina, Sofya V; Shchegolkov, Evgeny V; Borisevich, Sophia S; Burgart, Yanina V; Saloutin, Victor I; Charushin, Valery N.
Afiliación
  • Khudina OG; Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russia.
  • Grishchenko MV; Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russia.
  • Makhaeva GF; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry (IPAC RAS), Russian Academy of Sciences, Chernogolovka, Russia.
  • Kovaleva NV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry (IPAC RAS), Russian Academy of Sciences, Chernogolovka, Russia.
  • Boltneva NP; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry (IPAC RAS), Russian Academy of Sciences, Chernogolovka, Russia.
  • Rudakova EV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry (IPAC RAS), Russian Academy of Sciences, Chernogolovka, Russia.
  • Lushchekina SV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry (IPAC RAS), Russian Academy of Sciences, Chernogolovka, Russia.
  • Shchegolkov EV; Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia.
  • Borisevich SS; Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russia.
  • Burgart YV; Institute of Cyber Intelligence Systems, National Research Nuclear University MEPhI, Moscow, Russia.
  • Saloutin VI; Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russia.
  • Charushin VN; Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, Ekaterinburg, Russia.
Arch Pharm (Weinheim) ; 357(2): e2300447, 2024 Feb.
Article en En | MEDLINE | ID: mdl-38072670
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Butirilcolinesterasa / Enfermedad de Alzheimer / Aminoquinolinas Límite: Humans Idioma: En Revista: Arch Pharm (Weinheim) Año: 2024 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Alemania
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Butirilcolinesterasa / Enfermedad de Alzheimer / Aminoquinolinas Límite: Humans Idioma: En Revista: Arch Pharm (Weinheim) Año: 2024 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Alemania