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ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma.
Jagirdar, Kasturee; Portuallo, Marie E; Wei, Meihan; Wilhide, Matthew; Bravo Narula, Jeremy A; Robertson, Bailey M; Alicea, Gretchen M; Aguh, Crystal; Xiao, Min; Godok, Tetiana; Fingerman, Dylan; Brown, Gregory Schuyler; Herlyn, Meenhard; Elad, Vissy M; Guo, Xinyu; Toska, Eneda; Zabransky, Daniel J; Wubbenhorst, Bradley; Nathanson, Katherine L; Kwatra, Shawn; Goyal, Yogesh; Ji, Hongkai; Liu, Qin; Rebecca, Vito W.
Afiliación
  • Jagirdar K; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Portuallo ME; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Wei M; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Wilhide M; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Bravo Narula JA; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Robertson BM; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Alicea GM; Department of Chemical and Biomolecular Engineering, The Johns Hopkins Whiting School of Engineering, Baltimore, MD, USA.
  • Aguh C; Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Xiao M; The Wistar Institute, Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Philadelphia, PA, USA.
  • Godok T; The Wistar Institute, Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Philadelphia, PA, USA.
  • Fingerman D; The Wistar Institute, Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Philadelphia, PA, USA.
  • Brown GS; The Wistar Institute, Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Philadelphia, PA, USA.
  • Herlyn M; The Wistar Institute, Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Philadelphia, PA, USA.
  • Elad VM; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Guo X; Sidney Kimmel Comprehensive Cancer Center and Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Toska E; Sidney Kimmel Comprehensive Cancer Center and Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Zabransky DJ; Sidney Kimmel Comprehensive Cancer Center and Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Wubbenhorst B; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
  • Nathanson KL; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
  • Kwatra S; Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Goyal Y; Department of Cell and Developmental Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
  • Ji H; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Liu Q; The Wistar Institute, Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Philadelphia, PA, USA.
  • Rebecca VW; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. vrebecc2@jh.edu.
Oncogene ; 43(6): 395-405, 2024 Feb.
Article en En | MEDLINE | ID: mdl-38066089
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Melanoma Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Melanoma Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido