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Design and synthesis of the first PARP-1 and proteasome dual inhibitors to treat breast cancer.
He, Hualong; Yang, Wan; Shi, Yaojie; Chen, Xin; Chen, Xinyi; Hu, Xiang; Li, Xinyue; Yang, Yingyue; Liu, Zhihao; Ye, Tinghong; Wang, Ningyu; Yu, Luoting.
Afiliación
  • He H; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Yang W; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Shi Y; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Chen X; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
  • Chen X; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Hu X; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Li X; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Yang Y; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
  • Liu Z; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Ye T; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Wang N; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China. Electronic address: wangny-swjtu@swjtu.edu.cn.
  • Yu L; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address: yuluot@scu.edu.cn.
Eur J Med Chem ; 264: 115943, 2024 Jan 15.
Article en En | MEDLINE | ID: mdl-38039793
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Female / Humans Idioma: En Revista: Eur J Med Chem Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Female / Humans Idioma: En Revista: Eur J Med Chem Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia