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Epigenetic phenotype of plasma cell-free DNA in the prediction of early-onset preeclampsia.
He, Wei; Zhang, Yi; Wu, Kai; Wang, Yunan; Zhao, Xin; Lv, Lijuan; Ren, Congmian; Lu, Jiaqi; Yang, Jiexia; Yin, Aihua; Liu, Guocheng.
Afiliación
  • He W; The First Affiliated Hospital of Jinan University, Guangzhou, China.
  • Zhang Y; Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
  • Wu K; Euler Technology, Beijing, China.
  • Wang Y; Peking-Tsinghua Center of Life Sciences, Beijing, China.
  • Zhao X; School of Life Sciences, Peking University, Beijing, China.
  • Lv L; Euler Technology, Beijing, China.
  • Ren C; Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
  • Lu J; Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
  • Yang J; Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
  • Yin A; Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
  • Liu G; Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
J Obstet Gynaecol ; 43(2): 2282100, 2023 Dec.
Article en En | MEDLINE | ID: mdl-38038254
Early-onset preeclampsia is a potentially dangerous condition that can have a profound impact on the health of both the expectant mother and her unborn child. This condition is particularly concerning because it's challenging to predict who may be affected using conventional methods such as monitoring blood pressure. In our research, we've developed an innovative, non-invasive approach to predict the onset of early preeclampsia. We do this by analysing the genetic material of the developing baby, which can be found in the mother's blood. Our method has shown remarkable accuracy in our testing populations, and its implications are substantial. By providing an early warning system, this breakthrough can benefit pregnant women immensely. It means that early-onset preeclampsia can be identified and addressed well before it becomes a serious health threat. This allows for timely medical interventions and treatments, significantly improving the well-being of both mothers and their precious little ones.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia / Ácidos Nucleicos Libres de Células Límite: Adolescent / Adult / Female / Humans / Pregnancy Idioma: En Revista: J Obstet Gynaecol Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia / Ácidos Nucleicos Libres de Células Límite: Adolescent / Adult / Female / Humans / Pregnancy Idioma: En Revista: J Obstet Gynaecol Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido