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Stevia Polyphenols, Their Antimicrobial and Anti-Inflammatory Properties, and Inhibitory Effect on Digestive Enzymes.
Myint, Khaing Zar; Zhou, Zhuoyu; Shi, Qiandai; Chen, Junming; Dong, Xinyu; Xia, Yongmei.
Afiliación
  • Myint KZ; State Key Laboratory of Food Science and Resource, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
  • Zhou Z; Key Laboratory of Synthetic and Biological Colloids (Ministry of Education), School of Chemical and Materials Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
  • Shi Q; State Key Laboratory of Food Science and Resource, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
  • Chen J; Key Laboratory of Synthetic and Biological Colloids (Ministry of Education), School of Chemical and Materials Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
  • Dong X; State Key Laboratory of Food Science and Resource, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
  • Xia Y; Key Laboratory of Synthetic and Biological Colloids (Ministry of Education), School of Chemical and Materials Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China.
Molecules ; 28(22)2023 Nov 13.
Article en En | MEDLINE | ID: mdl-38005293
Polyphenols from stevia leaves (PPSs) are abundant byproducts from steviol glycoside production, which have been often studied as raw extracts from stevia extracts for their bioactivities. Herein, the PPSs rich in isochlorogenic acids were studied for their antimicrobial and anti-inflammatory properties, as well as their inhibitory effects on digestive enzymes. The PPSs presented stronger antibacterial activity against E. coli, S. aureus, P. aeruginosa, and B. subtilis than their antifungal activity against M. furfur and A. niger. Meanwhile, the PPSs inhibited four cancer cells by more than 60% based on their viability, in a dose-dependent manner. The PPSs presented similar IC50 values on the inhibition of digestive enzyme activities compared to epigallocatechin gallate (EGCG), but had weaker anti-inflammatory activity. Therefore, PPSs could be a potential natural alternative to antimicrobial agents. This is the first report on the bioactivity of polyphenols from stevia rebaudiana (Bertoni) leaves excluding flavonoids, and will be of benefit for understanding the role of PPSs and their application.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Stevia / Diterpenos de Tipo Kaurano Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Stevia / Diterpenos de Tipo Kaurano Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza