A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy.

Gong, Christine; Bertagnolli, Lynn N; Boulton, David W; Coppola, Paola

Gong, Christine; Bertagnolli, Lynn N; Boulton, David W; Coppola, Paola.

Afiliación

Gong C; School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Bertagnolli LN; AstraZeneca LP, Biopharmaceuticals R&D, Clinical Pharmacology & Safety Sciences, Clinical Pharmacology & Quantitative Pharmacology, Gaithersburg, MD 20878, USA.
Boulton DW; AstraZeneca LP, Biopharmaceuticals R&D, Clinical Pharmacology & Safety Sciences, Clinical Pharmacology & Quantitative Pharmacology, Gaithersburg, MD 20878, USA.
Coppola P; AstraZeneca LP, Biopharmaceuticals R&D, Clinical Pharmacology & Safety Sciences, Clinical Pharmacology & Quantitative Pharmacology, Cambridge CB2 0AA, UK.

Pharmaceutics ; 15(11)2023 Nov 15.

Article en En | MEDLINE | ID: mdl-38004602

Palabras clave

drug transporter; gestational change; phase II enzyme; physiologically based pharmacokinetic (PBPK) modeling; placenta; pregnancy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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