ADMET and Solubility Analysis of New 5-Nitroisatine-Based Inhibitors of CDK2 Enzymes.

Czelen, Przemyslaw; Jelinski, Tomasz; Skotnicka, Agnieszka; Szefler, Beata; Szupryczynski, Kamil

Czelen, Przemyslaw; Jelinski, Tomasz; Skotnicka, Agnieszka; Szefler, Beata; Szupryczynski, Kamil.

Afiliación

Czelen P; Department of Physical Chemistry, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Kurpinskiego 5, 85-096 Bydgoszcz, Poland.
Jelinski T; Department of Physical Chemistry, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Kurpinskiego 5, 85-096 Bydgoszcz, Poland.
Skotnicka A; Faculty of Chemical Technology and Engineering, Bydgoszcz University of Science and Technology, Seminaryjna 3, 85-326 Bydgoszcz, Poland.
Szefler B; Department of Physical Chemistry, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Kurpinskiego 5, 85-096 Bydgoszcz, Poland.
Szupryczynski K; Doctoral School of Medical and Health Sciences, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Jagiellonska 13, 85-067 Bydgoszcz, Poland.

Biomedicines ; 11(11)2023 Nov 10.

Article en En | MEDLINE | ID: mdl-38002019

Palabras clave

ADMET; CDK2; competitive inhibition; cosolvation; isatin; solubility

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biomedicines Año: 2023 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Suiza

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