Your browser doesn't support javascript.
loading
Pooled rates and demographics of POTS following SARS-CoV-2 infection versus COVID-19 vaccination: Systematic review and meta-analysis.
Yong, Shin Jie; Halim, Alice; Liu, Shiliang; Halim, Michael; Alshehri, Ahmad A; Alshahrani, Mohammed A; Alshahrani, Mohammed M; Alfaraj, Amal H; Alburaiky, Lamees M; Khamis, Faryal; AlShehail, Bashayer M; Alfaresi, Mubarak; Al Azmi, Reyouf; Albayat, Hawra; Al Kaabi, Nawal A; Alhajri, Mashael; Al Amri, Kawthar Amur Salim; Alsalman, Jameela; Algosaibi, Sarah A; Al Fares, Mona A; Almanaa, Taghreed N; Almutawif, Yahya A; Mohapatra, Ranjan K; Rabaan, Ali A.
Afiliación
  • Yong SJ; Department of Biological Sciences, School of Medical and Life Sciences, Sunway University, Selangor, Malaysia. Electronic address: shin.y7@imail.sunway.edu.my.
  • Halim A; Shanghai Medical College, Fudan University, Shanghai, China.
  • Liu S; Centre for Surveillance and Applied Research, Public Health Agency of Canada, Ontario, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Halim M; Department of Biomedical Science, School of Science, Engineering and Environment, University of Salford, Greater Manchester, United Kingdom.
  • Alshehri AA; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
  • Alshahrani MA; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
  • Alshahrani MM; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
  • Alfaraj AH; Pediatric Department, Abqaiq General Hospital, First Eastern Health Cluster, Abqaiq, Saudi Arabia.
  • Alburaiky LM; Pediatric Department, Safwa General Hospital, Eastern Health Cluster, Safwa, Saudi Arabia.
  • Khamis F; Infection Diseases unit, Department of Internal Medicine, The Royal Hospital, Muscat, Oman.
  • Muzaheed; Department of Clinical Laboratory Science, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
  • AlShehail BM; Pharmacy Practice Department, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
  • Alfaresi M; Department of Pathology and Laboratory Medicine, Zayed Military Hospital, Abu Dhabi, United Arab Emirates; Department of Pathology, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
  • Al Azmi R; Infection Prevention and Control, Eastern Health Cluster, Dammam, Saudi Arabia.
  • Albayat H; Infectious Disease Department, King Saud Medical City, Riyadh, Saudi Arabia.
  • Al Kaabi NA; Sheikh Khalifa Medical City, Abu Dhabi Health Services Company, Abu Dhabi, United Arab Emirates; College of Medicine and Health Science, Khalifa University, Abu Dhabi, United Arab Emirates.
  • Alhajri M; Department of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
  • Al Amri KAS; Infection and Control Department, Armed Forces Hospital, Azaibah, Oman.
  • Alsalman J; Infection Disease Unit, Department of Internal Medicine, Salmaniya Medical Complex, Ministry of Health, Manama, Bahrain.
  • Algosaibi SA; Academic and Clinical Training, Eastern Health Cluster, Rural Health Network, Dammam, Saudi Arabia.
  • Al Fares MA; Department of Internal Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
  • Almanaa TN; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
  • Almutawif YA; Department of Medical Laboratories Technology, College of Applied Medical Sciences, Taibah University, Madinah, Saudi Arabia.
  • Mohapatra RK; Department of Chemistry, Government College of Engineering, Keonjhar, India.
  • Rabaan AA; Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia; Department of Public Health and Nutrition, The University of Haripur, Haripur, Pakistan. Electronic address: arabaan@gmail.com.
Auton Neurosci ; 250: 103132, 2023 12.
Article en En | MEDLINE | ID: mdl-38000119
PURPOSE: To address recent concerns of postural orthostatic tachycardia syndrome (POTS) occurring after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccination. METHODS: We searched PubMed, Web of Science, and Scopus as of 1st June 2023. We performed a systematic review and meta-analysis of pooled POTS rate in SARS-CoV-2-infected and COVID-19-vaccinated groups from epidemiological studies, followed by subgroup analyses by characteristic. Meta-analysis of risk ratio was conducted to compare POTS rate in infected versus uninfected groups. Meta-analysis of demographics was also performed to compare cases of post-infection and post-vaccination POTS from case reports and series. RESULTS: We estimated the pooled POTS rate of 107.75 (95 % CI: 9.73 to 273.52) and 3.94 (95 % CI: 0 to 16.39) cases per 10,000 (i.e., 1.08 % and 0.039 %) in infected and vaccinated individuals based on 5 and 2 studies, respectively. Meta-regression revealed age as a significant variable influencing 86.2 % variance of the pooled POTS rate in infected population (P < 0.05). Moreover, POTS was 2.12-fold more likely to occur in infected than uninfected individuals (RR = 2.12, 95 % CI: 1.71 to 2.62, P < 0.001). Meta-analyzed demographics for cases of post-infection (n = 43) and post-vaccination (n = 17) POTS found no significant differences in several variables between groups, except that the time from exposure to symptom onset was shorter for cases of post-vaccination POTS (P < 0.05). CONCLUSION: Although evidence is limited for post-vaccination POTS, our study showed that POTS occur more frequently following SARS-CoV-2 infection than COVID-19 vaccination.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Taquicardia Postural Ortostática / COVID-19 Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: Auton Neurosci Asunto de la revista: NEUROLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Taquicardia Postural Ortostática / COVID-19 Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: Auton Neurosci Asunto de la revista: NEUROLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos