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Racial Disparities in Periprosthetic Joint Infections after Primary Total Joint Arthroplasty: A Retrospective Study.
Pinkney, Jodian A; Davis, Joshua B; Collins, Jamie E; Shebl, Fatma M; Jamison, Matthew P; Acosta Julbe, Jose I; Bogart, Laura M; Ojikutu, Bisola O; Chen, Antonia F; Nelson, Sandra B.
Afiliación
  • Pinkney JA; Massachusetts General Hospital, Boston, MA 02114, USA.
  • Davis JB; Harvard Medical School, Boston, MA 02115, USA.
  • Collins JE; Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Shebl FM; Harvard Medical School, Boston, MA 02115, USA.
  • Jamison MP; Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Acosta Julbe JI; Massachusetts General Hospital, Boston, MA 02114, USA.
  • Bogart LM; Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Ojikutu BO; Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Chen AF; RAND Corporation, Santa Monica, CA 90401, USA.
  • Nelson SB; Charles R. Drew University of Medicine and Science, Los Angeles, CA 90059, USA.
Antibiotics (Basel) ; 12(11)2023 Nov 16.
Article en En | MEDLINE | ID: mdl-37998831
In the United States, racial disparities have been observed in complications following total joint arthroplasty (TJA), including readmissions and mortality. It is unclear whether such disparities also exist for periprosthetic joint infection (PJI). The clinical data registry of a large New England hospital system was used to identify patients who underwent TJA between January 2018 and December 2021. The comorbidities were evaluated using the Elixhauser Comorbidity Index (ECI). We used Poisson regression to assess the relationship between PJI and race by estimating cumulative incidence ratios (cIRs) and 95% confidence intervals (CIs). We adjusted for age and sex and examined whether ECI was a mediator using structural equation modeling. The final analytic dataset included 10,018 TJAs in 9681 individuals [mean age (SD) 69 (10)]. The majority (96.5%) of the TJAs were performed in non-Hispanic (NH) White individuals. The incidence of PJI was higher among NH Black individuals (3.1%) compared with NH White individuals (1.6%) [adjusted cIR = 2.12, 95%CI = 1.16-3.89; p = 0.015]. Comorbidities significantly mediated the association between race and PJI, accounting for 26% of the total effect of race on PJI incidence. Interventions that increase access to high-quality treatments for comorbidities before and after TJA may reduce racial disparities in PJI.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Antibiotics (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Antibiotics (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza