Effect of primidone in somatic and germ cells of mice.
Toxicol Lett
; 34(2-3): 149-52, 1986 Dec.
Article
en En
| MEDLINE
| ID: mdl-3798475
Primidone, an anti-convulsant drug, was tested in mice for mutagenicity in somatic cells by the micronucleus test and in germ cells by the sperm-head abnormality assay. Mice were treated orally with the drug at doses of 4.37, 8.75 and 13.11 mg/mouse. The results indicate that the drug is capable of inducing mutations both in somatic and germ cells of mice.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Primidona
/
Células Germinativas
/
Mutágenos
Límite:
Animals
Idioma:
En
Revista:
Toxicol Lett
Año:
1986
Tipo del documento:
Article
Pais de publicación:
Países Bajos