Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway.

Cai, Tingwen; Chen, Siyuan; Wu, Chenghu; Lou, Chao; Wang, Weidan; Lin, Chihao; Jiang, Hongyi; Xu, Xinxian

Cai, Tingwen; Chen, Siyuan; Wu, Chenghu; Lou, Chao; Wang, Weidan; Lin, Chihao; Jiang, Hongyi; Xu, Xinxian.

Afiliación

Cai T; Department of Orthopedics, The Second Affiliated Hospital, Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Chen S; Key Laboratory of Orthopedics of Zhejiang Province, Wenzhou, Zhejiang Province, China.
Wu C; The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Lou C; Department of Orthopedics, The Second Affiliated Hospital, Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Wang W; Key Laboratory of Orthopedics of Zhejiang Province, Wenzhou, Zhejiang Province, China.
Lin C; The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Jiang H; School of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
Xu X; Department of Orthopedics, The Second Affiliated Hospital, Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.

BMC Musculoskelet Disord ; 24(1): 894, 2023 Nov 17.

Article en En | MEDLINE | ID: mdl-37978375

Asunto(s)

Eritropoyetina; Necrosis de la Cabeza Femoral; Ratas; Animales; Caspasa 3/metabolismo; Proteína X Asociada a bcl-2/metabolismo; Necrosis de la Cabeza Femoral/inducido químicamente; Necrosis de la Cabeza Femoral/tratamiento farmacológico; Necrosis de la Cabeza Femoral/metabolismo; Citocromos c/metabolismo; Citocromos c/farmacología; Microtomografía por Rayos X; Apoptosis; Transducción de Señal; Osteoblastos/metabolismo; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Eritropoyetina/farmacología; Esteroides/efectos adversos

Palabras clave

Apoptosis; Erythropoietin; Necrosis of the femoral head; STAT1-caspase 3

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eritropoyetina / Necrosis de la Cabeza Femoral Límite: Animals Idioma: En Revista: BMC Musculoskelet Disord Asunto de la revista: FISIOLOGIA / ORTOPEDIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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