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COVID-19 in hospitalized infants aged under 3 months: multi-center experiences across Turkey.
Üstündag, Gülnihan; Karadag-Oncel, Eda; Kara-Ulu, Nursel; Polat, Meltem; Sali, Enes; Çakir, Deniz; Sahin, Aslihan; Akaslan-Kara, Aybüke; Kaçar, Pelin; Isik, Aylin Dizi; Erdemli, Pinar Canizci; Durmus, Sevgi Yasar; Özdemir, Ahmet; Çelik, Binnaz; Sütçü, Murat; Kara, Manolya; Kandemir-Gülmez, Tugba; Çelikyurt, Aydin; Ümit, Zühal; Aktürk, Hacer; Arikan, Kamile; Kaba, Özge; Caymaz, Canan; Bayhan, Cihangül; Aygün, Deniz; Penezoglu, Döndü Nilay; Alatas, Silem Özdem; Özdemir, Halil; Türel, Özden; Akça, Mehtap; Çelebi-Çongur, Emel; Kepenekli, Eda; Çelik, Ümit; Ecevit, Ismail Zafer; Belet, Nursen; Dalgiç, Nazan; Yilmaz, Nisel; Yilmaz, Dilek; Kuyucu, Necdet; Çiftçi, Ergin.
Afiliación
  • Üstündag G; Izmir Tepecik Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Izmir, Turkey.
  • Karadag-Oncel E; Department of Pediatric Infectious Diseases, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey. dredakaradag@gmail.com.
  • Kara-Ulu N; Faculty of Medicine, Department of Pediatric Infectious Diseases, Gazi University, Ankara, Turkey.
  • Polat M; Faculty of Medicine, Department of Pediatric Infectious Diseases, Gazi University, Ankara, Turkey.
  • Sali E; Ümraniye Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Istanbul, Turkey.
  • Çakir D; Ümraniye Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Istanbul, Turkey.
  • Sahin A; Izmir Tepecik Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Izmir, Turkey.
  • Akaslan-Kara A; Izmir Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Izmir, Turkey.
  • Kaçar P; Izmir Behçet Uz Child Disease and Pediatric Surgery Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Izmir, Turkey.
  • Isik AD; Faculty of Medicine, Department of Pediatric Infectious Diseases, Marmara University, Istanbul, Turkey.
  • Erdemli PC; Faculty of Medicine, Department of Pediatric Infectious Diseases, Marmara University, Istanbul, Turkey.
  • Durmus SY; Clinic of Pediatric Infectious Disease, Kayseri City Hospital, Kayseri, Turkey.
  • Özdemir A; Clinic of Neonatal Intensive Care Unit, Kayseri City Hospital, Kayseri, Turkey.
  • Çelik B; Clinic of Pediatrics, Kayseri City Hospital, Kayseri, Turkey.
  • Sütçü M; Faculty of Medicine, Department of Pediatric Infectious Diseases, Istinye University, Istanbul, Turkey.
  • Kara M; Faculty of Medicine, Department of Pediatric Infectious Diseases, Istinye University, Istanbul, Turkey.
  • Kandemir-Gülmez T; Faculty of Medicine, Department of Pediatric Infectious Diseases, Yeditepe University, Istanbul, Turkey.
  • Çelikyurt A; Clinic of Pediatric Infectious Diseases, Adana City Hospital, Adana, Turkey.
  • Ümit Z; Faculty of Medicine, Department of Pediatrics, Koç University, Istanbul, Turkey.
  • Aktürk H; Clinic of Pediatric Infectious Diseases, Manisa City Hospital, Manisa, Turkey.
  • Arikan K; Faculty of Medicine, Department of Pediatric Infectious Diseases, Koç University, Istanbul, Turkey.
  • Kaba Ö; Clinic of Pediatric Infectious Diseases, Buca Seyfi Demirsoy Training and Research Hospital, Izmir, Turkey.
  • Caymaz C; Clinic of Pediatric Infectious Disease, Basaksehir Çam Ve Sakura City Hospital, Istanbul, Turkey.
  • Bayhan C; Clinic of Pediatric Infectious Disease, Basaksehir Çam Ve Sakura City Hospital, Istanbul, Turkey.
  • Aygün D; Gülhane Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Ankara, Turkey.
  • Penezoglu DN; Faculty of Medicine, Department of Pediatric Infectious Diseases, Cerrahpasa University Istanbul, Istanbul, Turkey.
  • Alatas SÖ; Faculty of Medicine, Department of Pediatric Infectious Diseases, Ankara University, Ankara, Turkey.
  • Özdemir H; Department of Pediatric Infectious Diseases, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.
  • Türel Ö; Faculty of Medicine, Department of Pediatric Infectious Diseases, Ankara University, Ankara, Turkey.
  • Akça M; Faculty of Medicine, Department of Pediatric Infectious Diseases, Bezmialem Foundation University, Istanbul, Turkey.
  • Çelebi-Çongur E; Faculty of Medicine, Department of Pediatric Infectious Diseases, Mersin University, Mersin, Turkey.
  • Kepenekli E; Sisli Hamidiye Etfal Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Istanbul, Turkey.
  • Çelik Ü; Faculty of Medicine, Department of Pediatric Infectious Diseases, Marmara University, Istanbul, Turkey.
  • Ecevit IZ; Clinic of Pediatric Infectious Diseases, Adana City Hospital, Adana, Turkey.
  • Belet N; Gülhane Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Ankara, Turkey.
  • Dalgiç N; Department of Pediatric Infectious Diseases, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.
  • Yilmaz N; Sisli Hamidiye Etfal Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Istanbul, Turkey.
  • Yilmaz D; Department of Medical Microbiology, Izmir Tepecik Training and Research Hospital, Health Sciences University, Izmir, Turkey.
  • Kuyucu N; Izmir Tepecik Training and Research Hospital, Clinic of Pediatric Infectious Diseases, Health Sciences University, Izmir, Turkey.
  • Çiftçi E; Faculty of Medicine, Department of Pediatric Infectious Diseases, Izmir Katip Çelebi University, Izmir, Turkey.
Eur J Pediatr ; 183(3): 1153-1162, 2024 Mar.
Article en En | MEDLINE | ID: mdl-37971516
To investigate coronavirus disease 2019 (COVID-19) in infants aged 0 to 3 months because there is currently a significant gap in the literature on the subject. A cross-sectional study was conducted with the involvement of 19 medical centers across Turkey and 570 infants. The majority of the patients were male (58.2%), and the three most common symptoms were fever (78.2%), cough (44.6%), and feeding intolerance (39.9%). The results showed that a small percentage of infants had positive blood (0.9%) or urine cultures (10.2%). Most infants presented with fever (78.2%). Children without underlying conditions (UCs) had mostly a complicated respiratory course and a normal chest radiography. Significant more positive urine culture rates were observed in infants with fever. A higher incidence of respiratory support requirements and abnormal chest findings were seen in infants with chronic conditions. These infants also had a longer hospital stay than those without chronic conditions.  Conclusions: Our study discloses the clinical observations and accompanying bacterial infections found in infants aged under 3 months with COVID-19. These findings can shed light on COVID-19 in infancy for physicians because there is limited clinical evidence available. What is Known: • COVID-19 in infants and older children has been seen more mildly than in adults. • The most common symptoms of COVID-19 in infants are fever and cough, as in older children and adults. COVID-19 should be one of the differential diagnoses in infants with fever. What is New: • Although most infants under three months had fever, the clinical course was uneventful and respiratory complications were rarely observed in healthy children. • Infants with underlying conditions had more frequent respiratory support and abnormal chest radiography and stayed longer in the hospital.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Límite: Female / Humans / Infant / Male / Newborn País/Región como asunto: Asia Idioma: En Revista: Eur J Pediatr Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Límite: Female / Humans / Infant / Male / Newborn País/Región como asunto: Asia Idioma: En Revista: Eur J Pediatr Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Alemania