Naturally occurring autoimmune disease in (NZB X NZW) F1 mice is correlated with suppression of MZ B cell development due to aberrant B Cell Receptor (BCR) signaling, which is exacerbated by exposure to inorganic mercury.

Gill, Randall F; Mathieu, Patricia A; Lash, Lawrence H; Rosenspire, Allen J

Gill, Randall F; Mathieu, Patricia A; Lash, Lawrence H; Rosenspire, Allen J.

Afiliación

Gill RF; Department of Biochemistry, Microbiology and Immunology, Wayne State University, Detroit MI.
Mathieu PA; Department of Pharmacology, Wayne State University, Detroit MI.
Lash LH; Department of Pharmacology, Wayne State University, Detroit MI.
Rosenspire AJ; Department of Biochemistry, Microbiology and Immunology, Wayne State University, Detroit MI.

Toxicol Sci ; 2023 Nov 11.

Article en En | MEDLINE | ID: mdl-37952249

Palabras clave

(NZB X NZW) F1 mice; Autoimmunity; B Cell Receptor (BCR) Signaling; Mercury (Hg2+); SLE

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Toxicol Sci Asunto de la revista: TOXICOLOGIA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

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