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COVID-19 among people living with HIV in Lebanon.
Noureldine, Hussein A; Chedid, Georges; Abdessamad, Hilal; Costanian, Christy; Maamari, Julian; Al Nakib, Mostafa; Maatook, Ismael; Farra, Anna; Husni, Roula; Mokhbat, Jacques.
Afiliación
  • Noureldine HA; College of Medicine, University of Central Florida, Orlando, Florida, USA.
  • Chedid G; HCA Florida North Florida Hospital, Graduate Medical Education Internal Medicine Residency Program, Gainesville, Florida, USA.
  • Abdessamad H; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
  • Costanian C; These authors have contributed equally to this work.
  • Maamari J; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
  • Al Nakib M; These authors have contributed equally to this work.
  • Maatook I; Department of Internal Medicine, Division of Infectious Diseases, Lebanese American University-Rizk Hospital, Beirut, Lebanon.
  • Farra A; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
  • Husni R; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
  • Mokhbat J; National AIDS Control Program, Ministry of Public Health, Lebanon.
East Mediterr Health J ; 29(10): 775-782, 2023 Nov 01.
Article en En | MEDLINE | ID: mdl-37947227
Background: There are conflicting reports of the interaction between COVID-19 and HIV infection among coinfected individuals, and there is a particular dearth of evidence among populations in the Middle East. Aim: To determine if living with HIV and use of antiretroviral therapy increases susceptibility to, and severity of, COVID-19. Methods: This cross-sectional study was based on telephone survey of COVID-19 symptoms duration and clinical course among 200 people living with HIV (PLWHs) and a review of medical records in Beirut, Lebanon, during Spring 2021. Data were collected from consenting patients using standardized forms. The laboratory and medical characteristics of PLWHs with and without COVID-19 were compared and the outcomes of COVID-19 were described. A binary logistic regression model for contracting COVID-19 was constructed based on clinically relevant covariates consistently associated with COVID-19. Significance level was set at 0.05 and statistical analysis was performed using SPSS version 27.0. The Lebanese American University Institutional Review Board approved the study protocol. Results: Fifty-two of 200 PLWHs contracted COVID-19 but only 4 progressed to severe COVID-19. No significant differences were found with respect to gender, time since HIV diagnosis, most recent CD4 count, viral load, substance use, comorbidities, or use of antiretroviral therapy. Older PLWHs were at lower risk of contracting COVID-19; COVID-19 infection was significantly associated with younger age. Conclusions: COVID-19 infection was associated with younger age among PLWHs in Lebanon, possibly due to behavioural and socioeconomic factors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / COVID-19 Límite: Humans País/Región como asunto: Asia Idioma: En Revista: East Mediterr Health J Asunto de la revista: MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Egipto

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / COVID-19 Límite: Humans País/Región como asunto: Asia Idioma: En Revista: East Mediterr Health J Asunto de la revista: MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Egipto