A New Dawn for Targeted Cancer Therapy: Small Molecule Covalent Binding Inhibitor Targeting K-Ras (G12C).

Li, Na; Liu, Chen-Fu; Zhang, Wen; Rao, Guo-Wu

Li, Na; Liu, Chen-Fu; Zhang, Wen; Rao, Guo-Wu.

Afiliación

Li N; College of Pharmaceutical Science, Zhejiang University of Technology, and Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
Liu CF; School of Pharmaceutical Sciences, Gannan Medical University, Ganzhou 341000, P. R. China.
Zhang W; College of Pharmaceutical Science, Zhejiang University of Technology, and Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
Rao GW; College of Pharmaceutical Science, Zhejiang University of Technology, and Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, P. R. China.

Curr Med Chem ; 2023 Nov 02.

Article en En | MEDLINE | ID: mdl-37936461

Palabras clave

Covalence; HSQC-NMR; Inhibitor; K-Ras(G12C); MAPK; NSCLC; SOS1; Switch I

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Curr Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article Pais de publicación: Emiratos Árabes Unidos

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